There are 8 ways to get from Lexington to Gainesville by car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Louisville International Airport, fly to Gainesville Regional Airport
best- Drive from Lexington to Louisville-Airport-SDFcar
- Fly from Louisville International Airport (SDF) to Gainesville Regional Airport (GNV)plane SDF - GNV
6h 54m$101–523Fly Blue Grass Airport to Gainesville Regional Airport
cheapest- Fly from Blue Grass Airport (LEX) to Gainesville Regional Airport (GNV)plane LEX - GNV
8h 51m$69–384Drive, bus via Nashville
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville Bus Station to Nashville Bus Stationbus
- Take the bus from Nashville Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Gainesvillebus
18h 27m$120–203Drive 685.5 mi
- Drive from Lexington to Gainesvillecar 685.5 mi
11h 58m$126–181Drive to Covington, fly to Orlando Sanford, drive
- Drive from Lexington to Covington (CVG)car
- Fly from Covington (CVG) to Orlando Sanford (SFB)plane CVG - SFB
- Drive from Orlando-Sanford-Airport-SFB to Gainesvillecar
5h 57m$135–652Fly Blue Grass Airport to Orlando Sanford, drive
- Fly from Blue Grass Airport (LEX) to Orlando Sanford (SFB)plane LEX - SFB
- Drive from Orlando-Sanford-Airport-SFB to Gainesvillecar
7h 11m$92–422Drive, bus
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Gainesvillebus
18h 32m$119–208Drive, bus #2
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Gainesville Bus Stopbus
21h 30m$126–220
Louisville International Airport (SDF) to Gainesville Regional Airport (GNV) flights
Comparing Your Travel Options
The cheapest way to get from Lexington to Gainesville is to drive and bus via Nashville which costs $120 - $210 and takes 18h 27m.
The fastest way to get from Lexington to Gainesville is to drive and fly which takes 5h 57m and costs $130 - $650.
The distance between Lexington and Gainesville is 710 miles. The road distance is 689.5 miles.
It takes approximately 6h 54m to get from Lexington to Gainesville, including transfers.
Yes, the driving distance between Lexington to Gainesville is 689 miles. It takes approximately 11h 58m to drive from Lexington to Gainesville.
There are 278+ hotels available in Gainesville.
What companies run services between Lexington, KY, USA and Gainesville, FL, USA?
Delta and American Airlines fly from Blue Grass Airport (LEX) to Gainesville Regional Airport (GNV) every 3 hours.
- Website
- allegiantair.com
Flights from Covington to Orlando Sanford
- Ave. Duration
- 2h 2m
- When
- Wednesday, Monday, Friday, Saturday, Thursday, and Sunday
- Estimated price
- $100–600
Flights from Blue Grass Airport to Orlando Sanford
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $70–390
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Louisville Bus Station to Nashville Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Every 4 hours
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- Every 4 hours
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Louisville Bus Station to Atlanta Bus Station
- Ave. Duration
- 8h 30m
- Frequency
- Every 4 hours
- Estimated price
- $65–110
- Website
- Greyhound
Bus from Louisville Bus Station to Atlanta Bus Station
- Ave. Duration
- 8h 30m
- Frequency
- Every 4 hours
- Estimated price
- $65–110
- Website
- Greyhound
Bus from Atlanta Bus Station to Gainesville Bus Stop
- Ave. Duration
- 6h 45m
- Frequency
- Once daily
- Estimated price
- $50–85
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide


