There are 5 ways to get from Lexington to Galena by plane, car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, drive
best- Fly from Blue Grass Airport (LEX) to Quad City International Airport (MLI)plane LEX - MLI
- Drive from Moline-Airport-MLI to Galenacar
9h 12m$73–376Drive, bus
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY to Chicago Union Stationbus
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to Dubuquebus
18h 13m$171–238Drive 526.1 mi
- Drive from Lexington to Galenacar 526.1 mi
9h 32m$96–139Drive, bus, train
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY to Chicago Union Stationbus
- Take the train from Chicago Union Station to Milwaukeetrain
- Take the bus from Milwaukee to Dubuquebus
18h 14m$203–272Drive, bus via Chicago
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY to Chicago Union Stationbus
- Take the bus from Chicago Bus Station to Madisonbus
- Take the bus from Madison to Dubuquebus
18h 49m$173–233
Blue Grass Airport (LEX) to Quad City International Airport (MLI) flights
Comparing Your Travel Options
The cheapest way to get from Lexington to Galena is to drive which costs $95 - $140 and takes 9h 32m.
The fastest way to get from Lexington to Galena is to fly and drive which takes 9h 12m and costs $70 - $380.
The distance between Lexington and Galena is 498 miles. The road distance is 529.2 miles.
It takes approximately 9h 12m to get from Lexington to Galena, including transfers.
Galena is 1h behind Lexington. It is currently 2:06 PM in Lexington and 1:06 PM in Galena.
Yes, the driving distance between Lexington to Galena is 529 miles. It takes approximately 9h 32m to drive from Lexington to Galena.
There are 118+ hotels available in Galena.
What companies run services between Lexington, KY, USA and Galena, IL, USA?
There is no direct connection from Lexington to Galena. However, you can take the line 3 bus to Transit Center, take the line 8 bus to Terminal @ Bluegrass Field, walk to Blue Grass Airport (LEX) airport, fly to Quad City International Airport (MLI), then drive to Galena. Alternatively, you can take a vehicle from Lexington to Galena via Middletown Station @ Target, S 5th @ W Jefferson, W Jefferson @ S 6th, W Broadway @ S 10th, Louisville, KY, Chicago Union Station, W Jackson Blvd, after S Clinton St, 250 N. Lake St - Madison UW Campus, Madison, and Dubuque in around 18h 13m.
- Website
- united.com
Flights from Blue Grass Airport to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $55–350
- Website
- aa.com
Flights from Blue Grass Airport to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $55–350
Flights from Blue Grass Airport to Quad City International Airport via Charlotte
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $85–440
Flights from Blue Grass Airport to Quad City International Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 23m
- When
- Every day
- Estimated price
- $110–550
- Website
- delta.com
Flights from Blue Grass Airport to Quad City International Airport via Atlanta
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $85–440
- Website
- allegiantair.com
Flights from Blue Grass Airport to Quad City International Airport via Punta Gorda
- Ave. Duration
- 7h 36m
- When
- Friday
- Estimated price
- $140–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Louisville, KY to Chicago Union Station
- Ave. Duration
- 6h
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- Amtrak
- Adult
- $50–60
Bus from Louisville, KY to Chicago Union Station
- Ave. Duration
- 6h
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- Amtrak
- Adult
- $50–60
Bus from Louisville, KY to Chicago Union Station
- Ave. Duration
- 6h
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- Amtrak
- Adult
- $50–60
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 40m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- Rockland Coaches
- Adult
- $25–55
- Phone
- 920 496 3600
- Website
- example.com
Bus from Madison to Dubuque
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $22–25
- Schedules at
- golamers.com
Bus from Milwaukee to Dubuque
- Ave. Duration
- 4h 25m
- Frequency
- Once daily
- Estimated price
- $34–39
- Schedules at
- golamers.com
Bus from Madison to Dubuque
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $22–25
- Schedules at
- golamers.com
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Madison
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- $27–45
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Chicago Bus Station to Madison
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $30–50
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide









