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How to get fromLexington to Hannibalby car, plane, taxi, bus, shuttle, or train

Find Transport to Hannibal

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There are 9 ways to get from Lexington to Hannibal by car, plane, taxi, bus, shuttle, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Louisville International Airport, fly to Quincy Regional Airport, taxi

    best
    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Quincy Regional Airport (UIN)plane plane SDF - UIN
    3. Take the taxi from Quincy Regional Airport (UIN) to Hannibaltaxi taxi
    5h 22m
    $134–406

  2. Fly Blue Grass Airport to Burlington Municipal Airport, drive

    cheapest
    1. Fly from Blue Grass Airport (LEX) to Burlington Municipal Airport (BRL)plane plane LEX - BRL
    2. Drive from Burlington Municipal Airport (BRL) to Hannibalcar car
    9h 32m
    $68–317

  3. Drive, bus, shuttle

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Evansville, INbus bus
    3. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    4. Take a shuttle bus from St. Louis to Hannibalshuttle bus
    14h 2m
    $109–170

  4. Drive, bus, train (Amtrak)

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Lafayette Amtrak Stationbus bus
    3. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Quincy Amtrak Stationtrain train
    17h 53m
    $244–428

  5. Drive 452.7 mi

    1. Drive from Lexington to Hannibalcar car 452.7 mi
    7h 52m
    $83–120

  6. Fly Blue Grass Airport to Columbia Regional Airport, shuttle

    1. Fly from Blue Grass Airport (LEX) to Columbia Regional Airport (COU)plane plane LEX - COU
    2. Take a shuttle bus from Columbia to Hannibalshuttle bus
    10h 17m
    $183–655

  7. Fly Blue Grass Airport to Quincy Regional Airport, taxi

    1. Fly from Blue Grass Airport (LEX) to Quincy Regional Airport (UIN)plane plane LEX - UIN
    2. Take the taxi from Quincy Regional Airport (UIN) to Hannibaltaxi taxi
    10h 3m
    $132–437

  8. Drive, bus to Nashville, fly to Quincy Regional Airport, taxi

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Nashvillebus bus
    3. Fly from Nashville (BNA) to Quincy Regional Airport (UIN)plane plane BNA - UIN
    4. Take the taxi from Quincy Regional Airport (UIN) to Hannibaltaxi taxi
    10h 25m
    $211–510

  9. Drive, bus

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Evansville, INbus bus
    3. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Quincy Public Transit Hubbus bus
    14h 31m
    $151–238

Louisville International Airport (SDF) to Quincy Regional Airport (UIN) flights

Calendar9Weekly Planes
Duration3h 57mAverage Duration
Ticket$52Cheapest Price
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Questions & Answers

Map of how to get from Lexington to Hannibal.ExpandLaunch map view
  • Distance: 422.8 mi
  • Duration: 5h 22m

What companies run services between Lexington, KY, USA and Hannibal, MO, USA?

There is no direct connection from Lexington to Hannibal. However, you can drive to Louisville-Airport-SDF airport, fly to Quincy Regional Airport (UIN), then take the taxi to Hannibal. Alternatively, you can take a vehicle from Lexington to Hannibal via Middletown Station @ Target, S 5th @ W Jefferson, W Jefferson @ S 6th, W Broadway @ S 10th, Louisville, KY, Evansville Bus Station, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, St. Louis, and Hannibal in around 14h 2m.

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