There are 6 ways to get from Lexington to Key West by car, plane, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Covington, fly
best- Drive from Lexington to Covington (CVG)car
- Fly from Covington (CVG) to Key West International Airport (EYW)plane CVG - EYW
4h 12m$126–515Fly from Blue Grass Airport
cheapest- Fly from Blue Grass Airport (LEX) to Key West International Airport (EYW)plane LEX - EYW
7h 19m$83–365Drive, bus, train
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY to Chicago Union Stationbus
- Take the train from Chicago Union Station to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
2d 16h$652–1,446Drive 1,155.6 mi
- Drive from Lexington to Key Westcar 1,155.6 mi
21h 5m$211–305Drive to Louisville International Airport, fly
- Drive from Lexington to Louisville-Airport-SDFcar
- Fly from Louisville International Airport (SDF) to Key West International Airport (EYW)plane SDF - EYW
5h 46m$110–464Drive to Mcghee Tyson Airport, fly
- Drive from Lexington to Mcghee Tyson Airport (TYS)car
- Fly from Mcghee Tyson Airport (TYS) to Key West International Airport (EYW)plane TYS - EYW
5h 24m$119–450
Covington (CVG) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Lexington to Key West is to fly which costs $80 - $370 and takes 7h 19m.
The fastest way to get from Lexington to Key West is to drive and fly which takes 4h 12m and costs $120 - $550.
The distance between Lexington and Key West is 1107 miles. The road distance is 1162.4 miles.
It takes approximately 4h 12m to get from Lexington to Key West, including transfers.
Yes, the driving distance between Lexington to Key West is 1162 miles. It takes approximately 21h 5m to drive from Lexington to Key West.
There are 972+ hotels available in Key West.
What companies run services between Lexington, KY, USA and Key West, FL, USA?
Delta, American Airlines, and United Airlines fly from Blue Grass Airport (LEX) to Key West International Airport (EYW) every 3 hours.
- Website
- aa.com
Flights from Covington to Key West International Airport via Miami
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $100–490
Flights from Covington to Key West International Airport via Charlotte
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $100–490
Flights from Louisville International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–450
Flights from Louisville International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 6h 56m
- When
- Every day
- Estimated price
- $95–450
Flights from Mcghee Tyson Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $80–400
Flights from Mcghee Tyson Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 13m
- When
- Thursday and Sunday
- Estimated price
- $80–410
Flights from Blue Grass Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 23m
- When
- Every day
- Estimated price
- $70–360
Flights from Blue Grass Airport to Key West International Airport via Philadelphia
- Ave. Duration
- 6h 37m
- When
- Every day
- Estimated price
- $100–460
Flights from Blue Grass Airport to Key West International Airport via Miami
- Ave. Duration
- 7h 12m
- When
- Thursday
- Estimated price
- $70–360
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Miami Amtrak Station
- Ave. Duration
- 46h 29m
- Frequency
- Once daily
- Estimated price
- $550–1,300
- Website
- Amtrak
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Louisville, KY to Chicago Union Station
- Ave. Duration
- 6h
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- Amtrak
- Adult
- $50–60
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide




