There are 2 ways to get from Lexington to Knoxville by car or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Louisville International Airport (SDF) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Lexington to Knoxville is to drive which costs $30 - $45 and takes 2h 52m.
The fastest way to get from Lexington to Knoxville is to drive which takes 2h 52m and costs $30 - $45.
The distance between Lexington and Knoxville is 169 miles. The road distance is 169 miles.
It takes approximately 2h 52m to drive 169 miles from Lexington to Knoxville.
Yes, the driving distance between Lexington to Knoxville is 169 miles. It takes approximately 2h 52m to drive from Lexington to Knoxville.
There are 290+ hotels available in Knoxville.
What companies run services between Lexington, KY, USA and Knoxville, TN, USA?
You can drive from Lexington to Knoxville in around 2h 52m.
- Website
- delta.com
Flights from Louisville International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $130–750
Flights from Louisville International Airport to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 5h 56m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–900
- Website
- aa.com
Flights from Louisville International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $140–800
- Website
- united.com
Flights from Louisville International Airport to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $190–950
- Website
- southwest.com
Flights from Louisville International Airport to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 5h 18m
- When
- Tuesday to Saturday
- Estimated price
- $100–700
- Website
- allegiantair.com
Flights from Louisville International Airport to Mcghee Tyson Airport via Valparaiso
- Ave. Duration
- 3h 53m
- When
- Sunday and Thursday
- Estimated price
- $200–950
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide