What is the cheapest way to get from Lexington to La Crosse?

The cheapest way to get from Lexington to La Crosse is to drive which costs $110 - $170 and takes 11h 13m.

What is the fastest way to get from Lexington to La Crosse?

The fastest way to get from Lexington to La Crosse is to drive and fly which takes 5h 40m and costs $110 - $600.

How far is it from Lexington to La Crosse?

The distance between Lexington and La Crosse is 570 miles. The road distance is 648.3 miles.

How long does it take to get from Lexington to La Crosse?

It takes approximately 5h 40m to get from Lexington to La Crosse, including transfers.

What is the time difference between Lexington and La Crosse?

La Crosse is 1h behind Lexington. It is currently 5:03 PM in Lexington and 4:03 PM in La Crosse.

Can I drive from Lexington to La Crosse?

Yes, the driving distance between Lexington to La Crosse is 648 miles. It takes approximately 11h 13m to drive from Lexington to La Crosse.

Where can I stay near La Crosse?

There are 47+ hotels available in La Crosse.

Lexington to La Crosse - 8 ways to travel via train, car, plane, and bus

There are 8 ways to get from Lexington to La Crosse by car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Drive to Covington, fly
best
1. Drive from Lexington to Covington (CVG)car
2. Fly from Covington (CVG) to La Crosse (LSE)plane CVG - LSE
5h 40m
$119–595
Fly from Blue Grass Airport
cheapest
1. Fly from Blue Grass Airport (LEX) to La Crosse (LSE)plane LEX - LSE
7h 17m
$81–395
Drive, bus, train (Amtrak)
1. Drive from Lexington to Middletown Station @ Targetcar
2. Take the bus from Louisville, KY to Chicago Union Stationbus
3. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain
15h 50m
$139–283
Drive, bus, train via Lafayette (Amtrak)
1. Drive from Lexington to Middletown Station @ Targetcar
2. Take the bus from Louisville, KY to Lafayette Amtrak Stationbus
3. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain
4. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain
18h 1m
$149–358
Drive 644.5 mi
1. Drive from Lexington to La Crossecar 644.5 mi
11h 13m
$118–170
Drive to Louisville International Airport, fly
1. Drive from Lexington to Louisville-Airport-SDFcar
2. Fly from Louisville International Airport (SDF) to La Crosse (LSE)plane SDF - LSE
7h 18m
$113–524
Drive, bus
1. Drive from Lexington to Middletown Station @ Targetcar
2. Take the bus from Louisville, KY to Chicago Union Stationbus
3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
4. Take the bus from Madison to La Crossebus
17h 29m
$124–193
Drive, bus via Indianapolis
1. Drive from Lexington to Middletown Station @ Targetcar
2. Take the bus from Louisville, KY to Indianapolis Union Stationbus
3. Take the bus from Indianapolis Union Station to Chicago Bus Stationbus
4. Take the bus from Chicago Bus Station to Madisonbus
5. Take the bus from Madison to La Crossebus
18h 51m
$126–218

Covington (CVG) to La Crosse (LSE) flights

42Weekly Planes

4h 54mAverage Duration

$86Cheapest Price

See schedules

Comparing Your Travel Options

Map of how to get from Lexington to La Crosse.

Launch map view

Distance: 566.3 mi
Duration: 5h 40m

What companies run services between Lexington, KY, USA and La Crosse, WI, USA?

American Airlines and United Airlines fly from Blue Grass Airport (LEX) to La Crosse (LSE) every 4 hours.

Airlines

Train operators

Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.