There are 4 ways to get from Lexington to Mechanicsburg by plane, car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Harrisburg International Airport
best- Fly from Blue Grass Airport (LEX) to Harrisburg International Airport (MDT)plane LEX - MDT
8h 39m$69–386Drive, bus
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Harrisburg Bus Stationbus
22h 15m$136–229Drive 520.4 mi
- Drive from Lexington to Mechanicsburgcar 520.4 mi
8h 54m$89–129Fly to Philadelphia International Airport, train
- Fly from Blue Grass Airport (LEX) to Philadelphia International Airport (PHL)plane LEX - PHL
- Take the train from 30th Street Station to Harrisburgtrain
9h 24m$135–528
Blue Grass Airport (LEX) to Harrisburg International Airport (MDT) flights
Comparing Your Travel Options
The cheapest way to get from Lexington to Mechanicsburg is to drive which costs $85 - $130 and takes 8h 54m.
The fastest way to get from Lexington to Mechanicsburg is to fly which takes 8h 39m and costs $65 - $390.
The distance between Lexington and Mechanicsburg is 483 miles. The road distance is 523.5 miles.
It takes approximately 8h 39m to get from Lexington to Mechanicsburg, including transfers.
Yes, the driving distance between Lexington to Mechanicsburg is 523 miles. It takes approximately 8h 54m to drive from Lexington to Mechanicsburg.
There are 170+ hotels available in Mechanicsburg.
What companies run services between Lexington, KY, USA and Mechanicsburg, Cumberland County, PA, USA?
Delta, American Airlines, and two other airlines fly from Blue Grass Airport (LEX) to Harrisburg International Airport (MDT) hourly.
- Website
- aa.com
Flights from Blue Grass Airport to Harrisburg International Airport via Charlotte
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $70–390
Flights from Blue Grass Airport to Harrisburg International Airport via Philadelphia International Airport
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $65–380
Flights from Blue Grass Airport to Harrisburg International Airport via Chicago O'Hare
- Ave. Duration
- 7h 6m
- When
- Every day
- Estimated price
- $85–430
Flights from Blue Grass Airport to Philadelphia International Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $75–430
Flights from Blue Grass Airport to Philadelphia International Airport via Charlotte
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $85–480
- Website
- delta.com
Flights from Blue Grass Airport to Harrisburg International Airport via Detroit
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $70–390
Flights from Blue Grass Airport to Harrisburg International Airport via Atlanta
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $85–430
Flights from Blue Grass Airport to Philadelphia International Airport via Detroit
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $90–480
Flights from Blue Grass Airport to Philadelphia International Airport via Atlanta
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $100–550
- Website
- united.com
Flights from Blue Grass Airport to Harrisburg International Airport via Chicago O'Hare
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $85–430
- Website
- allegiantair.com
Flights from Blue Grass Airport to Harrisburg International Airport via Orlando Sanford
- Ave. Duration
- 5h 55m
- When
- Thursday
- Estimated price
- $120–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Harrisburg
- Ave. Duration
- 1h 51m
- Frequency
- Every 2 hours
- Estimated price
- $55–90
- Website
- Amtrak
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Indianapolis Union Station to Harrisburg Bus Station
- Ave. Duration
- 14h
- Frequency
- Every 4 hours
- Estimated price
- $100–160
- Website
- Greyhound
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