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How to get fromLexington to Milwaukeeby car, bus, train, or plane

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There are 11 ways to get from Lexington to Milwaukee by car, bus, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, bus, train (Amtrak)

    best
    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Chicago Union Stationbus bus
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    12h 20m
    $86–133

  2. Fly Blue Grass Airport to Chicago O'Hare International Airport, bus

    cheapest
    1. Fly from Blue Grass Airport (LEX) to Chicago O'Hare International Airport (ORD)plane plane LEX - ORD
    2. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    7h 13m
    $55–298

  3. Drive 451 mi

    1. Drive from Lexington to Milwaukeecar car 451 mi
    8h 15m
    $83–119

  4. Fly Blue Grass Airport to General Mitchell International Airport

    1. Fly from Blue Grass Airport (LEX) to General Mitchell International Airport (MKE)plane plane LEX - MKE
    7h 34m
    $80–475

  5. Drive, bus

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Chicago Union Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    12h 40m
    $76–107

  6. Drive, bus via Lafayette

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Lafayette Amtrak Stationbus bus
    3. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    4. Take the bus from Multi-Modal/Rental Car Facility to Milwaukee Intermodal/Amtrak Stationbus bus
    13h 38m
    $137–190

  7. Drive, bus, train via Lafayette (Amtrak)

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Lafayette Amtrak Stationbus bus
    3. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Milwaukeetrain train
    14h 31m
    $96–198

  8. Drive to Covington, fly to Chicago O'Hare International Airport, bus

    1. Drive from Lexington to Covington (CVG)car car
    2. Fly from Covington (CVG) to Chicago O'Hare International Airport (ORD)plane plane CVG - ORD
    3. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    5h 31m
    $178–848

  9. Drive to Louisville International Airport, fly to Chicago O'Hare International Airport, bus

    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Chicago O'Hare International Airport (ORD)plane plane SDF - ORD
    3. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    5h 40m
    $72–367

  10. Drive to Louisville International Airport, fly to Chicago Midway International Airport, train

    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Chicago Midway International Airport (MDW)plane plane SDF - MDW
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    6h 7m
    $91–449

  11. Drive to Covington, fly to Chicago Midway International Airport, train

    1. Drive from Lexington to Covington (CVG)car car
    2. Fly from Covington (CVG) to Chicago Midway International Airport (MDW)plane plane CVG - MDW
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    6h 1m
    $192–440

Blue Grass Airport (LEX) to General Mitchell International Airport (MKE) flights

Calendar118Weekly Planes
Duration5h 38mAverage Duration
Ticket$76Cheapest Price
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Questions & Answers

Map of how to get from Lexington to Milwaukee.ExpandLaunch map view
  • Distance: 468 mi
  • Duration: 12h 20m

What companies run services between Lexington, KY, USA and Milwaukee, WI, USA?

United Airlines, American Airlines, and Delta fly from Blue Grass Airport (LEX) to General Mitchell International Airport (MKE) hourly.

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