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How to get fromLexington to Missouriby plane, car, bus, or train

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There are 7 ways to get from Lexington to Missouri by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Columbia Regional Airport

    best
    1. Fly from Blue Grass Airport (LEX) to Columbia Regional Airport (COU)plane plane LEX - COU
    8h 23m
    $117–457

  2. Fly to Springfield-Branson National Airport

    cheapest
    1. Fly from Blue Grass Airport (LEX) to Springfield-Branson National Airport (SGF)plane plane LEX - SGF
    8h 4m
    $93–432

  3. Drive, bus

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Evansville, INbus bus
    3. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    15h 31m
    $110–263

  4. Drive  583.9 mi

    1. Drive from Lexington to Kansas Citycar car 583.9 mi
    9h 56m
    $107–154

  5. Fly to Lambert–St. Louis International Airport

    1. Fly from Blue Grass Airport (LEX) to Lambert–St. Louis International Airport (STL)plane plane LEX - STL
    7h 46m
    $95–555

  6. Drive, bus via Indianapolis

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    15h 42m
    $106–193

  7. Drive, bus, train

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Evansville, INbus bus
    3. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    4. Take the train from St. Louis to Kansas Citytrain train
    17h 23m
    $140–368

Blue Grass Airport (LEX) to Columbia Regional Airport (COU) flights

Calendar56Weekly Planes
Duration5h 49mAverage Duration
Ticket$69Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lexington to Missouri.ExpandLaunch map view
  • Distance: 444.3 mi
  • Duration: 8h 23m

What companies run services between Lexington, KY, USA and Missouri, USA?

United Airlines and American Airlines fly from Blue Grass Airport (LEX) to Columbia Regional Airport (COU) every 4 hours.

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