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How to get fromLexington to Mount Pleasantby car, plane, or bus

Find Transport to Mount Pleasant

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There are 6 ways to get from Lexington to Mount Pleasant by car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Covington, fly

    best
    1. Drive from Lexington to Covington (CVG)car car
    2. Fly from Covington (CVG) to Charleston International Airport (CHS)plane plane CVG - CHS
    6h 6m
    $99–1,026

  2. Drive 517.6 mi

    cheapest
    1. Drive from Lexington to Mount Pleasantcar car 517.6 mi
    9h 45m
    $95–137

  3. Drive, bus via Nashville

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Nashvillebus bus
    3. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    5. Drive from Myrtle Beach Bus Station to S. Pinckney St / Society Rdcar car
    6. Take the bus from S. Pinckney St / Society Rd to East Cooper Medical Centerbus bus
    26h 6m
    $145–277

  4. Drive to Louisville International Airport, fly

    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Charleston International Airport (CHS)plane plane SDF - CHS
    6h 8m
    $358–425

  5. Fly from Blue Grass Airport

    1. Fly from Blue Grass Airport (LEX) to Charleston International Airport (CHS)plane plane LEX - CHS
    9h 43m
    $96–556

  6. Drive, bus

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    5. Drive from Myrtle Beach Bus Station to S. Pinckney St / Society Rdcar car
    6. Take the bus from S. Pinckney St / Society Rd to East Cooper Medical Centerbus bus
    32h 21m
    $182–357

Covington (CVG) to Charleston International Airport (CHS) flights

Calendar40Weekly Planes
Duration3h 23mAverage Duration
Ticket$80Cheapest Price
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Questions & Answers

Map of how to get from Lexington to Mount Pleasant.ExpandLaunch map view
  • Distance: 602.3 mi
  • Duration: 6h 6m

What companies run services between Lexington, KY, USA and Mount Pleasant, SC, USA?

American Airlines, Delta, and United Airlines fly from Blue Grass Airport (LEX) to Charleston International Airport (CHS) hourly.

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Bus operators

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