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How to get fromLexington to O'Fallonby car, plane, train, or bus

Find Transport to O'Fallon

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There are 6 ways to get from Lexington to O'Fallon by car, plane, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Louisville International Airport, fly, train

    best
    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL)plane plane SDF - STL
    3. Take the train from LAMBERT AIRPORT TERMINAL #1 station to SHILOH-SCOTT stationtrain train
    6h 57m
    $108–575

  2. Drive  321.3 mi

    cheapest
    1. Drive from Lexington to O'Falloncar car 321.3 mi
    5h 29m
    $59–85

  3. Drive, bus

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Evansville, INbus bus
    3. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    12h 8m
    $82–202

  4. Drive to Covington, fly, train

    1. Drive from Lexington to Covington (CVG)car car
    2. Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)plane plane CVG - STL
    3. Take the train from LAMBERT AIRPORT TERMINAL #1 station to SHILOH-SCOTT stationtrain train
    6h 56m
    $139–776

  5. Drive to John Glenn Columbus International Airport, fly, train

    1. Drive from Lexington to Columbus-Airport-CMHcar car
    2. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    3. Take the train from LAMBERT AIRPORT TERMINAL #1 station to SHILOH-SCOTT stationtrain train
    7h 2m
    $131–657

  6. Fly from Blue Grass Airport, train

    1. Fly from Blue Grass Airport (LEX) to Lambert–St. Louis International Airport (STL)plane plane LEX - STL
    2. Take the train from LAMBERT AIRPORT TERMINAL #1 station to SHILOH-SCOTT stationtrain train
    9h 12m
    $91–496

Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL) flights

Calendar104Weekly Planes
Duration4h 22mAverage Duration
Ticket$91Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lexington to O'Fallon.ExpandLaunch map view
  • Distance: 375.4 mi
  • Duration: 6h 57m

What companies run services between Lexington, KY, USA and O'Fallon, IL, USA?

There is no direct connection from Lexington to O'Fallon. However, you can drive to Louisville-Airport-SDF airport, fly to Lambert–St. Louis International Airport (STL), walk to LAMBERT AIRPORT TERMINAL #1 station, take the train to SHILOH-SCOTT station, walk to Shiloh-Scott Transit Center, then take the line 12 bus to State @ Cherry Wb. Alternatively, you can take a vehicle from Lexington to State @ Lincoln Eb via Middletown Station @ Target, S 5th @ W Jefferson, W Jefferson @ S 6th, W Broadway @ S 10th, Louisville, KY, Evansville Bus Station, St Louis Bus Station, CIVIC CENTER station, FAIRVIEW HEIGHTS station, and Fairview Heights Transit Center in around 12h 8m.

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