There are 9 ways to get from Lexington to Osage Beach by car, bus, train, taxi, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive, bus, train, taxi
best- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY to Evansville, INbus
- Take the bus from Evansville Bus Station to St Louis Bus Stationbus
- Take the train from St. Louis to Jefferson City Stationtrain
- Take the taxi from Jefferson City Station to Osage Beachtaxi
14h 46m$216–423Fly Blue Grass Airport to Columbia Regional Airport, drive
cheapest- Fly from Blue Grass Airport (LEX) to Columbia Regional Airport (COU)plane LEX - COU
- Drive from Columbia Regional Airport (COU) to Osage Beachcar
9h 34m$79–411Drive 496.6 mi
- Drive from Lexington to Osage Beachcar 496.6 mi
9h 4m$91–131Drive, bus, train, taxi via Louisville
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY to Evansville, INbus
- Take the bus from Evansville Bus Station to St Louis Bus Stationbus
- Take the train from St. Louis to Jefferson City Stationtrain
- Take the taxi from Jefferson City Station to Osage Beachtaxi
14h 53m$216–423Drive, bus, shuttle, taxi
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY to Evansville, INbus
- Take the bus from Evansville Bus Station to St Louis Bus Stationbus
- Take a shuttle bus from St Louis International Airport to Ft Wood - St Robert - Waynesville
- Take the taxi from Ft Wood - St Robert - Waynesville to Osage Beachtaxi
16h 7m$324–491Drive, bus, taxi
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY to Evansville, INbus
- Take the bus from Evansville Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Jefferson Citybus
- Take the taxi from Jefferson City to Osage Beachtaxi
16h 28m$213–383Fly Blue Grass Airport to Springfield-Branson National Airport, drive
- Fly from Blue Grass Airport (LEX) to Springfield-Branson National Airport (SGF)plane LEX - SGF
- Drive from Springfield-Branson National Airport (SGF) to Osage Beachcar
9h 1m$94–437Drive to Louisville International Airport, fly to Waynesville-St. Robert Regional Airport, taxi
- Drive from Lexington to Louisville-Airport-SDFcar
- Fly from Louisville International Airport (SDF) to Waynesville-St. Robert Regional Airport (TBN)plane SDF - TBN
- Take the taxi from Waynesville-St. Robert Regional Airport (TBN) to Osage Beachtaxi
9h 37m$254–781Drive to Covington, fly to Waynesville-St. Robert Regional Airport, taxi
- Drive from Lexington to Covington (CVG)car
- Fly from Covington (CVG) to Waynesville-St. Robert Regional Airport (TBN)plane CVG - TBN
- Take the taxi from Waynesville-St. Robert Regional Airport (TBN) to Osage Beachtaxi
9h 36m$265–832
Blue Grass Airport (LEX) to Columbia Regional Airport (COU) flights
Comparing Your Travel Options
The cheapest way to get from Lexington to Osage Beach is to drive which costs $90 - $140 and takes 9h 4m.
The fastest way to get from Lexington to Osage Beach is to fly and drive which takes 9h 1m and costs $90 - $440.
The distance between Lexington and Osage Beach is 544 miles. The road distance is 499.5 miles.
It takes approximately 14h 46m to get from Lexington to Osage Beach, including transfers.
Osage Beach is 1h behind Lexington. It is currently 5:18 AM in Lexington and 4:18 AM in Osage Beach.
Yes, the driving distance between Lexington to Osage Beach is 499 miles. It takes approximately 9h 4m to drive from Lexington to Osage Beach.
There are 942+ hotels available in Osage Beach.
What companies run services between Lexington, KY, USA and Osage Beach, MO, USA?
There is no direct connection from Lexington to Osage Beach. However, you can drive to Middletown Station @ Target, take the line 31 bus to S 5th @ W Jefferson, walk to W Jefferson @ S 6th, take the line 10 bus to W Broadway @ S 10th, walk to Louisville, KY, take the bus to Evansville, IN, take the bus to St Louis Bus Station, walk to St. Louis, take the train to Jefferson City Station, then take the taxi to Osage Beach. Alternatively, you can drive from Lexington to Osage Beach in around 9h 4m.
- Website
- aa.com
Flights from Blue Grass Airport to Columbia Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $100–550
Flights from Blue Grass Airport to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 34m
- When
- Every day
- Estimated price
- $65–390
Flights from Blue Grass Airport to Columbia Regional Airport via Charlotte
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $85–450
Flights from Blue Grass Airport to Springfield-Branson National Airport via Chicago O'Hare
- Ave. Duration
- 5h 33m
- When
- Every day
- Estimated price
- $75–410
Flights from Blue Grass Airport to Springfield-Branson National Airport via Charlotte
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $90–450
Flights from Blue Grass Airport to Springfield-Branson National Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $100–480
- Website
- contouraviation.com
Flights from Louisville International Airport to Waynesville-St. Robert Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $130–650
Flights from Louisville International Airport to Waynesville-St. Robert Regional Airport via Nashville
- Ave. Duration
- 9h 30m
- When
- Monday, Thursday, and Friday
- Estimated price
- $190–800
Flights from Louisville International Airport to Waynesville-St. Robert Regional Airport via Atlanta, Nashville
- Ave. Duration
- 6h 54m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
Flights from Louisville International Airport to Waynesville-St. Robert Regional Airport via Chicago Midway, Nashville
- Ave. Duration
- 8h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $120–600
Flights from Louisville International Airport to Waynesville-St. Robert Regional Airport via Charlotte, Nashville
- Ave. Duration
- 8h 34m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–600
Flights from Louisville International Airport to Waynesville-St. Robert Regional Airport via Detroit, Nashville
- Ave. Duration
- 8h 50m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Covington to Waynesville-St. Robert Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $150–750
Flights from Covington to Waynesville-St. Robert Regional Airport via Nashville
- Ave. Duration
- 9h 40m
- When
- Monday, Wednesday, Thursday, and Friday
- Estimated price
- $230–950
Flights from Covington to Waynesville-St. Robert Regional Airport via Atlanta, Nashville
- Ave. Duration
- 6h 46m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Covington to Waynesville-St. Robert Regional Airport via Chicago Midway, Nashville
- Ave. Duration
- 7h 55m
- When
- Sunday
- Estimated price
- $120–650
Flights from Covington to Waynesville-St. Robert Regional Airport via Detroit, Nashville
- Ave. Duration
- 8h 40m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–700
- Website
- united.com
Flights from Blue Grass Airport to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $65–390
Flights from Blue Grass Airport to Springfield-Branson National Airport via Chicago O'Hare
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $75–410
Flights from Blue Grass Airport to Springfield-Branson National Airport via Denver
- Ave. Duration
- 8h 25m
- When
- Every day
- Estimated price
- $130–600
- Website
- delta.com
Flights from Blue Grass Airport to Springfield-Branson National Airport via Atlanta
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $80–430
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Louis to Jefferson City Station
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $30–85
- Website
- Amtrak
Train from St. Louis to Jefferson City Station
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $30–85
- Website
- Amtrak
- Phone
- +1 502-368-5644 x 135
- Website
- Miller Transportation
Bus from Louisville, KY to Evansville, IN
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–130
- Website
- Miller Transportation
Bus from Louisville, KY to Evansville, IN
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–130
- Website
- Miller Transportation
Bus from Louisville, KY to Evansville, IN
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–130
- Website
- Miller Transportation
Bus from Louisville, KY to Evansville, IN
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–130
- Website
- Miller Transportation
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Evansville Bus Station to St Louis Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Evansville Bus Station to St Louis Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Evansville Bus Station to St Louis Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Evansville Bus Station to St Louis Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $27–45
- Website
- Greyhound
Bus from St Louis Bus Station to Jefferson City
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $27–45
- Website
- Greyhound
- Phone
- 573-368-4656
- [email protected]
- Website
- USA Express
Shuttle from St Louis International Airport to Ft Wood - St Robert - Waynesville
- Ave. Duration
- 2h 45m
- Frequency
- 4 times a day
- Estimated price
- $135–150
- Website
- USA Express
- Ave. Duration
- 1h 3m
- Estimated price
- $110–160
Checker Cab
- Phone
- +1-573-636-7101
Checker Cab
- Phone
- +1-573-636-7101
Checker Cab
- Phone
- +1-573-636-7101
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