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How to get fromLexington to Panama City Beachby car, plane, or bus

Find Transport to Panama City Beach

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There are 7 ways to get from Lexington to Panama City Beach by car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Louisville International Airport, fly to Northwest Florida Beaches International Airport

    best
    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Northwest Florida Beaches International Airport (ECP)plane plane SDF - ECP
    5h 15m
    $144–526

  2. Drive to Louisville International Airport, fly to Destin–Fort Walton Beach Airport, drive

    cheapest
    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Destin–Fort Walton Beach Airport (VPS)plane plane SDF - VPS
    3. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    4h 35m
    $99–467

  3. Drive, bus

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Nashvillebus bus
    3. Take the bus from Nashville Bus Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    20h 30m
    $138–255

  4. Drive 636.4 mi

    1. Drive from Lexington to Panama City Beachcar car 636.4 mi
    12h 7m
    $117–168

  5. Drive to Covington, fly to Destin–Fort Walton Beach Airport, drive

    1. Drive from Lexington to Covington (CVG)car car
    2. Fly from Covington (CVG) to Destin–Fort Walton Beach Airport (VPS)plane plane CVG - VPS
    3. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    4h 41m
    $115–538

  6. Fly Blue Grass Airport to Northwest Florida Beaches International Airport

    1. Fly from Blue Grass Airport (LEX) to Northwest Florida Beaches International Airport (ECP)plane plane LEX - ECP
    6h 57m
    $147–617

  7. Fly Blue Grass Airport to Destin–Fort Walton Beach Airport, drive

    1. Fly from Blue Grass Airport (LEX) to Destin–Fort Walton Beach Airport (VPS)plane plane LEX - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    7h 56m
    $112–568

Louisville International Airport (SDF) to Northwest Florida Beaches International Airport (ECP) flights

Calendar66Weekly Planes
Duration4h 44mAverage Duration
Ticket$79Cheapest Price
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Questions & Answers

Map of how to get from Lexington to Panama City Beach.ExpandLaunch map view
  • Distance: 638.7 mi
  • Duration: 5h 15m

What companies run services between Lexington, KY, USA and Panama City Beach, FL, USA?

Delta, American Airlines, and United Airlines fly from Blue Grass Airport (LEX) to Northwest Florida Beaches International Airport (ECP) every 3 hours.

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