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How to get fromLexington to Panama Cityby car or plane

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There are 6 ways to get from Lexington to Panama City by car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Louisville International Airport, fly to Northwest Florida Beaches International Airport

    best
    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Northwest Florida Beaches International Airport (ECP)plane plane SDF - ECP
    5h 20m
    $159–541

  2. Drive to Louisville International Airport, fly to Destin–Fort Walton Beach Airport, drive

    cheapest
    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Destin–Fort Walton Beach Airport (VPS)plane plane SDF - VPS
    3. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    4h 49m
    $101–469

  3. Drive 631.4 mi

    1. Drive from Lexington to Panama Citycar car 631.4 mi
    11h 51m
    $116–167

  4. Drive to Covington, fly to Destin–Fort Walton Beach Airport, drive

    1. Drive from Lexington to Covington (CVG)car car
    2. Fly from Covington (CVG) to Destin–Fort Walton Beach Airport (VPS)plane plane CVG - VPS
    3. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    4h 54m
    $117–540

  5. Fly Blue Grass Airport to Northwest Florida Beaches International Airport

    1. Fly from Blue Grass Airport (LEX) to Northwest Florida Beaches International Airport (ECP)plane plane LEX - ECP
    7h 3m
    $162–632

  6. Fly Blue Grass Airport to Destin–Fort Walton Beach Airport, drive

    1. Fly from Blue Grass Airport (LEX) to Destin–Fort Walton Beach Airport (VPS)plane plane LEX - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    8h 9m
    $114–570

Louisville International Airport (SDF) to Northwest Florida Beaches International Airport (ECP) flights

Calendar73Weekly Planes
Duration4h 51mAverage Duration
Ticket$79Cheapest Price
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Questions & Answers

Map of how to get from Lexington to Panama City.ExpandLaunch map view
  • Distance: 642.9 mi
  • Duration: 5h 20m

What companies run services between Lexington, KY, USA and Panama City, FL, USA?

Delta, American Airlines, and United Airlines fly from Blue Grass Airport (LEX) to Northwest Florida Beaches International Airport (ECP) every 3 hours.

Airlines

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