There are 5 ways to get from Lexington to Roanoke by car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Louisville International Airport, fly to Roanoke Regional Airport-Woodrum Field
best- Drive from Lexington to Louisville-Airport-SDFcar
- Fly from Louisville International Airport (SDF) to Roanoke Regional Airport-Woodrum Field (ROA)plane SDF - ROA
6h 13m$98–506Fly Blue Grass Airport to Roanoke Regional Airport-Woodrum Field
cheapest- Fly from Blue Grass Airport (LEX) to Roanoke Regional Airport-Woodrum Field (ROA)plane LEX - ROA
7h 40m$61–357Drive, bus
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY to Nashvillebus
- Take the bus from Nashville Bus Station to Roanoke Bus Stopbus
16h 11m$119–193Drive 342.7 mi
- Drive from Lexington to Roanokecar 342.7 mi
6h 8m$63–91Fly Blue Grass Airport to Greenbrier Valley Airport, drive
- Fly from Blue Grass Airport (LEX) to Greenbrier Valley Airport (LWB)plane LEX - LWB
- Drive from Greenbrier Valley Airport (LWB) to Roanokecar
9h 29m$69–371
Louisville International Airport (SDF) to Roanoke Regional Airport-Woodrum Field (ROA) flights
Comparing Your Travel Options
The cheapest way to get from Lexington to Roanoke is to drive which costs $60 - $95 and takes 6h 8m.
The fastest way to get from Lexington to Roanoke is to drive which takes 6h 8m and costs $60 - $95.
The distance between Lexington and Roanoke is 409 miles. The road distance is 344.7 miles.
It takes approximately 6h 13m to get from Lexington to Roanoke, including transfers.
Yes, the driving distance between Lexington to Roanoke is 345 miles. It takes approximately 6h 8m to drive from Lexington to Roanoke.
There are 94+ hotels available in Roanoke.
What companies run services between Lexington, KY, USA and Roanoke, VA, USA?
American Airlines, Delta, and United Airlines fly from Blue Grass Airport (LEX) to Roanoke Regional Airport-Woodrum Field (ROA) every 3 hours.
- Website
- aa.com
Flights from Louisville International Airport to Roanoke Regional Airport-Woodrum Field via Charlotte
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $80–480
Flights from Louisville International Airport to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $100–600
Flights from Louisville International Airport to Roanoke Regional Airport-Woodrum Field via Philadelphia
- Ave. Duration
- 7h 5m
- When
- Every day
- Estimated price
- $110–600
Flights from Blue Grass Airport to Roanoke Regional Airport-Woodrum Field via Charlotte
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $55–350
Flights from Blue Grass Airport to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $80–430
Flights from Blue Grass Airport to Roanoke Regional Airport-Woodrum Field via Philadelphia
- Ave. Duration
- 6h 23m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- $80–420
Flights from Blue Grass Airport to Greenbrier Valley Airport via Charlotte
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $55–350
Flights from Blue Grass Airport to Greenbrier Valley Airport via Chicago O'Hare
- Ave. Duration
- 6h 9m
- When
- Monday, Friday, and Sunday
- Estimated price
- $80–420
Flights from Blue Grass Airport to Greenbrier Valley Airport via Philadelphia, Charlotte
- Ave. Duration
- 8h 14m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- $100–480
- Website
- delta.com
Flights from Louisville International Airport to Roanoke Regional Airport-Woodrum Field via Atlanta
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $95–550
Flights from Blue Grass Airport to Roanoke Regional Airport-Woodrum Field via Atlanta
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $70–390
- Website
- united.com
Flights from Louisville International Airport to Roanoke Regional Airport-Woodrum Field via Washington Dulles
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $90–550
Flights from Louisville International Airport to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $100–600
Flights from Blue Grass Airport to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 6h 53m
- When
- Every day
- Estimated price
- $80–430
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Louisville, KY to Nashville
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Amtrak
- Adult
- $30–50
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Nashville Bus Station to Roanoke Bus Stop
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Greyhound
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