There are 6 ways to get from Lexington to Seneca by car, plane, taxi, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive 318.7 mi
best- Drive from Lexington to Senecacar 318.7 mi
6h 54m$59–84Fly Blue Grass Airport to Greenville–Spartanburg International Airport, taxi
- Fly from Blue Grass Airport (LEX) to Greenville–Spartanburg International Airport (GSP)plane LEX - GSP
- Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi
7h 28m$212–722Fly Blue Grass Airport to Asheville Regional Airport, drive
- Fly from Blue Grass Airport (LEX) to Asheville Regional Airport (AVL)plane LEX - AVL
- Drive from Asheville-Airport-AVL to Senecacar
8h 15m$64–361Drive to Louisville International Airport, fly to Hartsfield-Jackson Atlanta International Airport, bus, taxi
- Drive from Lexington to Louisville-Airport-SDFcar
- Fly from Louisville International Airport (SDF) to Hartsfield-Jackson Atlanta International Airport (ATL)plane SDF - ATL
- Take the bus from Atlanta to Flying J - Commercebus
- Take the taxi from Flying J - Commerce to Senecataxi
7h 34m$204–664Fly Blue Grass Airport to Hartsfield-Jackson Atlanta International Airport, bus, taxi
- Fly from Blue Grass Airport (LEX) to Hartsfield-Jackson Atlanta International Airport (ATL)plane LEX - ATL
- Take the bus from Atlanta to Flying J - Commercebus
- Take the taxi from Flying J - Commerce to Senecataxi
9h 2m$177–555Fly Blue Grass Airport to Charlotte Douglas International Airport, train
- Fly from Blue Grass Airport (LEX) to Charlotte Douglas International Airport (CLT)plane LEX - CLT
- Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain
10h 1m$175–628
Blue Grass Airport (LEX) to Greenville–Spartanburg International Airport (GSP) flights
Comparing Your Travel Options
The cheapest way to get from Lexington to Seneca is to drive which costs $55 - $85 and takes 6h 54m.
The fastest way to get from Lexington to Seneca is to drive which takes 6h 54m and costs $55 - $85.
The distance between Lexington and Seneca is 321 miles. The road distance is 320.6 miles.
It takes approximately 6h 54m to drive 320.6 miles from Lexington to Seneca.
Yes, the driving distance between Lexington to Seneca is 321 miles. It takes approximately 6h 54m to drive from Lexington to Seneca.
There are 172+ hotels available in Seneca.
What companies run services between Lexington, KY, USA and Seneca, SC, USA?
You can drive from Lexington to Seneca in around 6h 54m.
- Website
- delta.com
Flights from Blue Grass Airport to Greenville–Spartanburg International Airport via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $90–550
Flights from Blue Grass Airport to Greenville–Spartanburg International Airport via Detroit
- Ave. Duration
- 7h 44m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Blue Grass Airport to Asheville Regional Airport via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $55–350
Flights from Louisville International Airport to Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $70–470
Flights from Blue Grass Airport to Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $55–380
Flights from Blue Grass Airport to Charlotte Douglas International Airport via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- $90–550
- Website
- aa.com
Flights from Blue Grass Airport to Greenville–Spartanburg International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $80–550
Flights from Blue Grass Airport to Greenville–Spartanburg International Airport via Chicago O'Hare
- Ave. Duration
- 6h 16m
- When
- Every day
- Estimated price
- $130–700
Flights from Blue Grass Airport to Asheville Regional Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $50–340
Flights from Blue Grass Airport to Asheville Regional Airport via Chicago O'Hare
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $80–430
Flights from Blue Grass Airport to Hartsfield-Jackson Atlanta International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 45m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–420
Flights from Blue Grass Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $70–470
- Website
- united.com
Flights from Blue Grass Airport to Greenville–Spartanburg International Airport via Chicago O'Hare
- Ave. Duration
- 5h 47m
- When
- Every day
- Estimated price
- $130–700
Flights from Blue Grass Airport to Asheville Regional Airport via Chicago O'Hare
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $80–430
- Website
- allegiantair.com
Flights from Blue Grass Airport to Greenville–Spartanburg International Airport via Orlando Sanford
- Ave. Duration
- 5h 8m
- When
- Thursday
- Estimated price
- $150–750
- Website
- southwest.com
Flights from Louisville International Airport to Hartsfield-Jackson Atlanta International Airport via Nashville
- Ave. Duration
- 3h 10m
- When
- Sunday
- Estimated price
- $75–480
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charlotte Amtrak Station to Clemson Amtrak Station
- Ave. Duration
- 3h 12m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Amtrak
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Atlanta to Flying J - Commerce
- Ave. Duration
- 1h 52m
- Frequency
- Once daily
- Estimated price
- $17–40
- Schedules at
- Tornado Bus Company
- Adult
- $17–40
Bus from Atlanta to Flying J - Commerce
- Ave. Duration
- 1h 52m
- Frequency
- Once daily
- Estimated price
- $17–40
- Schedules at
- Tornado Bus Company
- Adult
- $17–40
- Ave. Duration
- 53 min
- Estimated price
- $100–170
GVL Taxi
- Phone
- +1 864-920-3352
- Website
- gvltaxi.com
Personal Touch Transportation
- Phone
- +18645250420
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Checker Cab
- Phone
- +1 864-583-2721
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