What is the cheapest way to get from Lexington to Sikeston?

The cheapest way to get from Lexington to Sikeston is to drive which costs $55 - $85 and takes 5h 30m.

What is the fastest way to get from Lexington to Sikeston?

The fastest way to get from Lexington to Sikeston is to drive which takes 5h 30m and costs $55 - $85.

How far is it from Lexington to Sikeston?

The distance between Lexington and Sikeston is 422 miles. The road distance is 320 miles.

How long does it take to get from Lexington to Sikeston?

It takes approximately 11h 26m to get from Lexington to Sikeston, including transfers.

What is the time difference between Lexington and Sikeston?

Sikeston is 1h behind Lexington. It is currently 3:08 PM in Lexington and 2:08 PM in Sikeston.

Can I drive from Lexington to Sikeston?

Yes, the driving distance between Lexington to Sikeston is 320 miles. It takes approximately 5h 30m to drive from Lexington to Sikeston.

Where can I stay near Sikeston?

There are 12+ hotels available in Sikeston.

Lexington to Sikeston - 4 ways to travel via car, bus, and plane

How to get fromLexington to Sikeston

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There are 4 ways to get from Lexington to Sikeston by car, bus, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Drive, bus via Clarksville Park & Ride
best
1. Drive from Lexington to Middletown Station @ Targetcar
2. Take the bus from Louisville Bus Station to Clarksville Park & Ridebus
3. Take the bus from Clarksville Park & Ride to Paducah Bus Stationbus
4. Drive from Paducah Bus Station to Sikestoncar
11h 26m
$63–111
Drive 318.1 mi
cheapest
1. Drive from Lexington to Sikestoncar 318.1 mi
5h 30m
$59–84
Fly, drive
1. Fly from Blue Grass Airport (LEX) to Barkley Regional Airport (PAH)plane LEX - PAH
2. Drive from Barkley Regional Airport (PAH) to Sikestoncar
9h 19m
$82–407
Drive, bus
1. Drive from Lexington to Middletown Station @ Targetcar
2. Take the bus from La Tropicana - Louisville, KY to Tornado Bus Co - West Memphisbus
3. Take the bus from Tornado Bus Co - West Memphis to Flying J - Matthewsbus
15h 31m
$149–213

Blue Grass Airport (LEX) to Barkley Regional Airport (PAH) flights

21Weekly Planes

6h 50mAverage Duration

$72Cheapest Price

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Questions & Answers

Map of how to get from Lexington to Sikeston.

Launch map view

Distance: 419.2 mi
Duration: 11h 26m

What companies run services between Lexington, KY, USA and Sikeston, MO, USA?

There is no direct connection from Lexington to Sikeston. However, you can drive to Middletown Station @ Target, take the line 31 bus to S 5th @ W Jefferson, walk to S Roy Wilkins @ W Muhammad Ali, take the line 10 bus to W Broadway @ S 10th, walk to Louisville Bus Station, take the bus to Clarksville Park & Ride, take the bus to Paducah Bus Station, then drive to Sikeston. Alternatively, you can drive from Lexington to Sikeston in around 5h 30m.

Airlines

Bus operators

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