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How to get fromLexington to Winston-Salemby plane, car, or bus

Find Transport to Winston-Salem

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There are 8 ways to get from Lexington to Winston-Salem by plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Blue Grass Airport to Piedmont Triad International Airport

    best
    1. Fly from Blue Grass Airport (LEX) to Piedmont Triad International Airport (GSO)plane plane LEX - GSO
    7h 29m
    $121–675

  2. Drive  348.1 mi

    cheapest
    1. Drive from Lexington to Winston-Salemcar car 348.1 mi
    7h
    $64–92

  3. Drive, bus

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville to Columbusbus bus
    3. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    18h 27m
    $109–188

  4. Drive to Louisville International Airport, fly to Charlotte Douglas International Airport, bus

    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Charlotte Douglas International Airport (CLT)plane plane SDF - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    6h 14m
    $115–667

  5. Drive to Covington, fly to Charlotte Douglas International Airport, bus

    1. Drive from Lexington to Covington (CVG)car car
    2. Fly from Covington (CVG) to Charlotte Douglas International Airport (CLT)plane plane CVG - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    6h 15m
    $126–718

  6. Drive to Tri-State Airport, fly to Charlotte Douglas International Airport, bus

    1. Drive from Lexington to Tri-State Airport (HTS)car car
    2. Fly from Tri-State Airport (HTS) to Charlotte Douglas International Airport (CLT)plane plane HTS - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    6h 40m
    $93–507

  7. Drive to Covington, fly to Raleigh-Durham International Airport, bus

    1. Drive from Lexington to Covington (CVG)car car
    2. Fly from Covington (CVG) to Raleigh-Durham International Airport (RDU)plane plane CVG - RDU
    3. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    7h 17m
    $123–598

  8. Fly Blue Grass Airport to Charlotte Douglas International Airport, bus

    1. Fly from Blue Grass Airport (LEX) to Charlotte Douglas International Airport (CLT)plane plane LEX - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    7h 44m
    $78–488

Blue Grass Airport (LEX) to Piedmont Triad International Airport (GSO) flights

Calendar99Weekly Planes
Duration5h 19mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

Map of how to get from Lexington to Winston-Salem.ExpandLaunch map view
  • Distance: 327.9 mi
  • Duration: 7h 29m

What companies run services between Lexington, KY, USA and Winston-Salem, NC, USA?

American Airlines, Delta, and United Airlines fly from Blue Grass Airport (LEX) to Piedmont Triad International Airport (GSO) hourly.

Airlines
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