There are 10 ways to get from Lille to Siena by train, plane, train (Eurostar, TGV, Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Brussels Airport, fly to Florence Peretola Airport, train
best- Take the train from Lille Europe to Brussel-Zuid / Bruxelles-Miditrain
- Fly from Brussels Airport (BRU) to Florence Peretola Airport (FLR)plane BRU - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 12m€93–288Train to Brussels South Charleroi Airport, fly to Pisa International Airport, train
cheapest- Take the train from Lille Flandres to Charleroi-Centraltrain
- Fly from Brussels South Charleroi Airport (CRL) to Pisa International Airport (PSA)plane CRL - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
8h 5m€75–263Train
- Take the train from Lille Europe to Chambery Challes Les Eauxtrain
- Take the train from Chambery Challes Les Eaux to Torino Porta Susatrain Tgv
- Take the train from Torino Porta Susa to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
13h 10m€301–568Bus
- Take the bus from Lille to Brussels-North train stationbus 328 / ...
- Take the bus from Bruxelles - Rue du Progrès to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Sienabus 443 / ...
21h 41mDrive 1,281 km
- Drive from Lille to Sienacar 1,281 km
13h 54m€199–288Train to Paris Charles De Gaulle Airport, fly to Florence Peretola Airport, train
- Take the train from Lille Europe to Aeroport Cdg2 Tgv Roissytrain
- Fly from Paris Charles De Gaulle Airport (CDG) to Florence Peretola Airport (FLR)plane CDG - FLR
- Take the train from Firenze S.M.N. to Sienatrain
6h 56m€137–331Train to Brussels South Charleroi Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Lille Flandres to Charleroi-Centraltrain
- Fly from Brussels South Charleroi Airport (CRL) to Bologna Guglielmo Marconi Airport (BLQ)plane CRL - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 36m€78–319Train, bus to Beauvais–Tillé Airport, fly to Pisa International Airport
- Take the train from Lille Flandres to Amienstrain
- Take the bus from Gare routière to Aéroportbus
- Fly from Beauvais–Tillé Airport (BVA) to Pisa International Airport (PSA)plane BVA - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
9h 34m€94–263Train to Brussels Airport, fly to Milan Linate Airport, train
- Take the train from Lille Europe to Brussel-Zuid / Bruxelles-Miditrain
- Fly from Brussels Airport (BRU) to Milan Linate Airport (LIN)plane BRU - LIN
- Take the train from Milano Rogoredo to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 57m€98–371Bus via Paris
- Take the bus from Lille - Europe Train Station to Paris - Bercy-Seine Bus Stationbus BlaBlaCar Bus
- Take the bus from Paris - Bercy-Seine Bus Station to Sienabus BlaBlaCar Bus
25h 25m€138–266
Lille to Siena by train
Questions & Answers
The cheapest way to get from Lille to Siena is to train and fly which costs €75 - €270 and takes 8h 5m.
The fastest way to get from Lille to Siena is to train and fly which takes 6h 56m and costs €130 - €340.
No, there is no direct bus from Lille to Siena. However, there are services departing from Lille and arriving at Siena via Bruxelles - Rue du Progrès and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 21h 41m.
No, there is no direct train from Lille to Siena. However, there are services departing from Lille Europe and arriving at Siena via Chambery Challes Les Eaux, Torino Porta Susa and Firenze S.M.N.. The journey, including transfers, takes approximately 13h 10m.
The distance between Lille and Siena is 1156 km. The road distance is 1281 km.
The best way to get from Lille to Siena without a car is to train which takes 13h 10m and costs €300 - €600.
It takes approximately 7h 12m to get from Lille to Siena, including transfers.
Lille to Siena bus services, operated by FlixBus, depart from Lille station.
Lille to Siena train services, operated by Eurostar, depart from Lille Europe station.
The best way to get from Lille to Siena is to train which takes 13h 10m and costs €300 - €600. Alternatively, you can bus, which costs and takes 21h 41m.
What companies run services between Lille, France and Siena, Italy?
You can take a train from Lille Europe to Siena via Chambery Challes Les Eaux, Torino Porta Susa, and Firenze S.M.N. in around 13h 10m. Alternatively, you can take a bus from Lille to Siena via Brussels-North train station, Bruxelles - Rue du Progrès, and Florence Villa Constanza Bus Station in around 21h 41m.
- Website
- klm.com
Flights from Brussels Airport to Florence Peretola Airport via Amsterdam Schiphol
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- €70–360
Flights from Paris Charles De Gaulle Airport to Florence Peretola Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- €60–360
Flights from Brussels Airport to Milan Linate Airport via Amsterdam Schiphol
- Ave. Duration
- 3h 35m
- When
- Saturday and Sunday
- Estimated price
- €55–300
- Website
- ryanair.com
Flights from Brussels South Charleroi Airport to Pisa International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €30–180
Flights from Brussels South Charleroi Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €30–240
Flights from Brussels South Charleroi Airport to Bologna Guglielmo Marconi Airport via Vienna
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, and Friday
- Estimated price
- €30–240
Flights from Beauvais–Tillé Airport to Pisa International Airport
- Ave. Duration
- 1h 45m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €50–180
- Website
- airfrance.com
Flights from Paris Charles De Gaulle Airport to Florence Peretola Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- €60–360
- Website
- brusselsairlines.com
Flights from Brussels Airport to Florence Peretola Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €90–200
Flights from Brussels Airport to Milan Linate Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- €70–290
- Website
- lufthansa.com
Flights from Brussels Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- €90–260
Flights from Brussels Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 25m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- €90–260
Flights from Paris Charles De Gaulle Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- €75–400
Flights from Brussels Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 3h 35m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- €190–310
- Website
- ita-airways.com
Flights from Brussels Airport to Milan Linate Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- €70–290
- Website
- swiss.com
Flights from Brussels Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- €80–200
Flights from Paris Charles De Gaulle Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €80–250
- Website
- easyjet.com
Flights from Brussels Airport to Milan Linate Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €35–170
- Website
- vueling.com
Flights from Brussels Airport to Florence Peretola Airport
- Ave. Duration
- 1h 50m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- €50–200
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Lille Europe to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €21–35
- Website
- TGV inOui
Train from Chambery Challes Les Eaux to Torino Porta Susa
- Ave. Duration
- 2h 39m
- Frequency
- Every 4 hours
- Estimated price
- €40–65
- Website
- TGV inOui
Train from Lille Europe to Aeroport Cdg2 Tgv Roissy
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- €40–65
- Website
- TGV inOui
Train from Lille Europe to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €21–35
- Website
- TGV inOui
- Phone
- +44 (0)3432 186 186
- Website
- Eurostar
Train from Lille Europe to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 39 min
- Frequency
- Hourly
- Estimated price
- €30–55
- Website
- Eurostar
Train from Lille Europe to Chambery Challes Les Eaux
- Ave. Duration
- 4h 8m
- Frequency
- Twice a week
- Estimated price
- €210–360
- Website
- Eurostar
Train from Lille Europe to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 39 min
- Frequency
- Hourly
- Estimated price
- €30–55
- Website
- Eurostar
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Lille Europe to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 48 min
- Frequency
- Twice daily
- Estimated price
- €17–40
- Website
- Belgian Railways
Train from Lille Europe to Aeroport Cdg2 Tgv Roissy
- Ave. Duration
- 59 min
- Frequency
- 3 times a day
- Estimated price
- €30–70
- Website
- Belgian Railways
Train from Lille Flandres to Charleroi-Central
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- €19–40
- Website
- Belgian Railways
Train from Lille Flandres to Charleroi-Central
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- €19–40
- Website
- Belgian Railways
Train from Lille Europe to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 48 min
- Frequency
- Twice daily
- Estimated price
- €17–40
- Website
- Belgian Railways
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Chambery Challes Les Eaux to Torino Porta Susa
- Ave. Duration
- 2h 34m
- Frequency
- 4 times a day
- Estimated price
- €24–40
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–10
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–13
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–10
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–13
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Torino Porta Susa to Firenze S.M.N.
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- €65–130
- Schedules at
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 15 minutes
- Estimated price
- €13–27
- Schedules at
- Trenitalia Frecce
Train from Milano Rogoredo to Firenze S.M.N.
- Ave. Duration
- 1h 45m
- Frequency
- Every 30 minutes
- Estimated price
- €40–90
- Schedules at
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Torino Porta Susa to Firenze S.M.N.
- Ave. Duration
- 3h 23m
- Frequency
- Once daily
- Estimated price
- €55–120
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- 5 times a day
- Estimated price
- €11–23
- Website
- Italo Treno
Train from Milano Rogoredo to Firenze S.M.N.
- Ave. Duration
- 1h 53m
- Frequency
- 4 times a day
- Estimated price
- €35–75
- Website
- Italo Treno
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Lille Europe to Aeroport Cdg2 Tgv Roissy
- Ave. Duration
- 1h 6m
- Frequency
- 3 times a day
- Estimated price
- €30–70
- Website
- Oui.SNCF
Train from Lille Flandres to Amiens
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €21–45
- Website
- Oui.SNCF
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €9–21
- Website
- Trenitalia Intercity
Train from Milano Rogoredo to Firenze S.M.N.
- Ave. Duration
- 3h 26m
- Frequency
- Twice daily
- Estimated price
- €30–70
- Website
- Trenitalia Intercity
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Lille to Brussels-North train station
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- €8–14
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €5–9
- Website
- Flixbus
Bus from Lille - Europe Train Station to Paris - Bercy-Seine Bus Station
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- €18–30
- Website
- Flixbus
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Bruxelles - Rue du Progrès to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 6m
- Frequency
- Once a week
- Website
- Onebus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €5–11
- Website
- BlaBlaCar Bus
Bus from Lille - Europe Train Station to Paris - Bercy-Seine Bus Station
- Ave. Duration
- 3h 35m
- Frequency
- Every 30 minutes
- Estimated price
- €20–40
- Website
- BlaBlaCar Bus
Bus from Paris - Bercy-Seine Bus Station to Siena
- Ave. Duration
- 20h 50m
- Frequency
- Once daily
- Estimated price
- €120–230
- Website
- BlaBlaCar Bus
- Phone
- 09 70 15 01 50
- [email protected]
- Website
- Oise - Réseau de l'Oise
Bus from Gare routière to Aéroport
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- €1
- Website
- Oise - Réseau de l'Oise
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
More Questions & Answers
Lille to Siena bus services, operated by FlixBus, arrive at Brussels-North train station.
Lille to Siena train services, operated by Eurostar, arrive at Chambery Challes Les Eaux station.
Yes, the driving distance between Lille to Siena is 1281 km. It takes approximately 13h 54m to drive from Lille to Siena.
Book your Lille to Siena train tickets online with Omio.
Book your Lille to Siena bus tickets online with Omio.
There are 2528+ hotels available in Siena.



















































