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How to get fromLisle to Charlotteby train, plane, bus, train (Amtrak), car, or bus (Amtrak, Greyhound)

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There are 8 ways to get from Lisle to Charlotte by train, plane, bus, train (Amtrak), car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly

    best
    1. Take the train from Lisle to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Charlotte Douglas International Airport (CLT)plane plane ORD - CLT
    5h 48m
    $130–404

  2. Bus

    cheapest
    1. Take the bus from Chicago to N Wilson Rd & Ferrell Pl - Columbusbus bus Chicago / ...
    2. Take the bus from Columbus to Charlottebus bus Bsb 32
    20h 57m
    $80–186

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Carytrain train Floridian
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train Piedmont / ...
    30h 22m
    $325–751

  4. Drive  756 mi

    1. Drive from Lisle to Charlottecar car 756 mi
    13h 19m
    $138–200

  5. Train to Chicago Midway International Airport, fly

    1. Take the train from Lisle to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Charlotte Douglas International Airport (CLT)plane plane MDW - CLT
    5h 32m
    $120–664

  6. Train to South Bend, fly

    1. Take the train from Van Buren St. to South Bend Airporttrain train
    2. Fly from South Bend (SBN) to Charlotte Douglas International Airport (CLT)plane plane SBN - CLT
    7h 55m
    $125–629

  7. Train to General Mitchell International Airport, fly

    1. Take the train from Chicago Union Station to Milwaukeetrain train
    2. Fly from General Mitchell International Airport (MKE) to Charlotte Douglas International Airport (CLT)plane plane MKE - CLT
    7h 50m
    $162–823

  8. Bus via Toledo

    1. Take the bus from Chicago Union Station to Toledobus bus Amtrak Thruway Connecting Service
    2. Take the bus from Toledo Bus Stop to Charlotte Bus Stationbus bus Greyhound US0140
    23h 36m
    $167–268

Lisle to Charlotte by train, foot, and bus

Calendar7Weekly Services
Duration20h 57mAverage Duration
Ticket$80Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lisle to Charlotte.ExpandLaunch map view
  • Distance: 649.4 mi
  • Duration: 5h 48m

What companies run services between Lisle, IL, USA and Charlotte, NC, USA?

You can take a train from Lisle to Charlotte via Chicago Union Station, Chicago, and Columbus in around 20h 57m. Alternatively, you can take a train from Lisle to Charlotte Amtrak Station via Chicago Union Station and Cary in around 30h 22m.

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