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How to get fromLisle to Louisvilleby bus, plane, bus (Amtrak), train, car, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Lisle to Louisville by bus, plane, bus (Amtrak), train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 330 bus to Chicago O'Hare International Airport, fly to Louisville International Airport

    best
    1. Take the bus from La Grange/Burlington Ave. to Rosemont CTA Station - Bus Stop Fbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    5h 13m
    $79–495

  2. Bus

    cheapest
    1. Take the bus from Chicago Bus Station to Louisville Bus Stationbus bus Greyhound US0100
    10h 2m
    $51–82

  3. Bus via Lafayette (Amtrak)

    1. Take the bus from Chicago Union Station to Lafayette Amtrak Stationbus bus Chicago
    2. Take the bus from Lafayette Amtrak Station to Louisville, KYbus bus Chicago
    9h 33m
    $58–101

  4. Train, bus

    1. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus Greyhound US0100 / ...
    9h 42m
    $72–171

  5. Drive  307.8 mi

    1. Drive from Lisle to Louisvillecar car 307.8 mi
    5h 26m
    $57–82

  6. Train to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the train from Lisle to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    5h 20m
    $103–714

  7. Fly Chicago O'Hare International Airport to Blue Grass Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 20m
    $61–321

Lisle to Louisville by train and bus (Amtrak)

Calendar7Weekly Services
Duration9h 33mAverage Duration
Ticket$58Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lisle to Louisville.ExpandLaunch map view
  • Distance: 318.4 mi
  • Duration: 5h 13m

What companies run services between Lisle, IL, USA and Louisville, KY, USA?

You can take a train from Lisle to Louisville, KY via Chicago Union Station, Chicago Union Station, and Lafayette Amtrak Station in around 9h 33m.

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Bus operators

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