Rome2Rio

How to get fromLisle to Louisvilleby bus (Greyhound, Amtrak), train, bus, car, or plane

Find Transport to Louisville

See all options

There are 6 ways to get from Lisle to Louisville by bus (Greyhound, Amtrak), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus Greyhound US0100 / ...
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    8h 37m
    $52–101

  2. Train, bus (Amtrak)

    1. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    10h 17m
    $77–171

  3. Drive  307.8 mi

    1. Drive from Lisle to Louisvillecar car 307.8 mi
    5h 26m
    $57–82

  4. Train to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the train from Lisle to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    5h 20m
    $93–614

  5. Train to Chicago O'Hare International Airport, fly to Louisville International Airport

    1. Take the train from Lisle to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    5h 41m
    $73–454

  6. Train to Chicago O'Hare International Airport, fly to Blue Grass Airport, drive

    1. Take the train from Lisle to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 52m
    $65–320

Lisle to Louisville by train, foot, and bus

Calendar14Weekly Services
Duration8h 37mAverage Duration
Ticket$52Cheapest Price
See schedules

Questions & Answers

Map of how to get from Lisle to Louisville.ExpandLaunch map view
  • Distance: 319.5 mi
  • Duration: 8h 37m

What companies run services between Lisle, IL, USA and Louisville, KY, USA?

You can take a train from Lisle to Louisville, KY via Chicago Union Station, Chicago Bus Station, and Indianapolis Union Station in around 8h 37m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers