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How to get fromLisle to Pittsburghby train, bus, plane, train (Amtrak), bus (Flixbus), car, subway, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Lisle to Pittsburgh by train, bus, plane, train (Amtrak), bus (Flixbus), car, subway, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, line 330 bus to Chicago O'Hare International Airport, fly to Pittsburgh International Airport, bus

    best
    1. Take the train from Lisle to LaGrange Roadtrain train
    2. Take the bus from La Grange/Burlington Ave. to Rosemont CTA Stationbus bus
    3. Fly from Chicago O'Hare International Airport (ORD) to Pittsburgh International Airport (PIT)plane plane ORD - PIT
    4. Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus bus
    5h 39m

  2. Bus

    cheapest
    1. Take the bus from Chicago Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0164
    14h 16m
    $76–147

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train Floridian
    11h 23m
    $155–326

  4. Bus via Auburn Gresham (Flixbus)

    1. Take the bus from Chicago to Pittsburgh Intermodal Stationbus bus FlixBus N2640
    13h 14m
    $87–151

  5. Drive 477.6 mi

    1. Drive from Lisle to Pittsburghcar car 477.6 mi
    8h 7m
    $88–126

  6. Train, subway to Chicago Midway International Airport, fly to Pittsburgh International Airport, bus

    1. Take the train from Lisle to Chicago Union Stationtrain train
    2. Take the subway from LaSalle/Van Buren to Midwaysubway subway
    3. Fly from Chicago Midway International Airport (MDW) to Pittsburgh International Airport (PIT)plane plane MDW - PIT
    4. Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus bus
    5h 47m

  7. Fly Chicago O'Hare International Airport to Johnstown-Cambria County Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Johnstown-Cambria County Airport (JST)plane plane ORD - JST
    2. Take the train from Johnstown Amtrak Station to Pittsburgh Amtrak Stationtrain train
    7h 30m
    $102–410

  8. Fly Chicago O'Hare International Airport to Morgantown Municipal Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Morgantown Municipal Airport (MGW)plane plane ORD - MGW
    2. Take the bus from Morgantown Mountaineer Station WVU to Pittsburgh Intermodal Stationbus bus
    6h 51m
    $84–377

Lisle to Pittsburgh by train (Amtrak)

Calendar7Weekly Trains
Duration11h 23mAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

Map of how to get from Lisle to Pittsburgh.ExpandLaunch map view
  • Distance: 462.3 mi
  • Duration: 5h 39m

What companies run services between Lisle, IL, USA and Pittsburgh, PA, USA?

Amtrak operates a train from Chicago Union Station to Pittsburgh Amtrak Station once daily. Tickets cost $150–320 and the journey takes 9h 25m. Alternatively, Flixbus USA operates a bus from Chicago to Pittsburgh Intermodal Station 6 times a week. Tickets cost $80–140 and the journey takes 10h 35m.

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