Rome2Rio

How to get fromLisle to Pittsburghby train, bus, plane, train (Amtrak), bus (Flixbus), car, subway, or bus (Greyhound, Flixbus)

Find Transport to Pittsburgh

See all options

There are 8 ways to get from Lisle to Pittsburgh by train, bus, plane, train (Amtrak), bus (Flixbus), car, subway, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, line 330 bus to Chicago O'Hare International Airport, fly to Pittsburgh International Airport, bus

    best
    1. Take the train from Lisle to LaGrange Roadtrain train
    2. Take the bus from La Grange/Burlington Ave. to Rosemont CTA Station - Bus Stop Fbus bus
    3. Fly from Chicago O'Hare International Airport (ORD) to Pittsburgh International Airport (PIT)plane plane ORD - PIT
    4. Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus bus
    5h 35m

  2. Bus

    cheapest
    1. Take the bus from Chicago Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0164
    14h 22m
    $76–127

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train Floridian
    11h 23m
    $115–286

  4. Bus via Auburn Gresham (Flixbus)

    1. Take the bus from Chicago to Pittsburgh Intermodal Stationbus bus FlixBus N2640
    13h 14m
    $82–131

  5. Drive  477.6 mi

    1. Drive from Lisle to Pittsburghcar car 477.6 mi
    8h 7m
    $88–126

  6. Train, subway to Chicago Midway International Airport, fly to Pittsburgh International Airport, bus

    1. Take the train from Lisle to Chicago Union Stationtrain train
    2. Take the subway from LaSalle/Van Buren to Midwaysubway subway
    3. Fly from Chicago Midway International Airport (MDW) to Pittsburgh International Airport (PIT)plane plane MDW - PIT
    4. Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus bus
    5h 47m

  7. Fly Chicago O'Hare International Airport to Johnstown-Cambria County Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Johnstown-Cambria County Airport (JST)plane plane ORD - JST
    2. Take the train from Johnstown Amtrak Station to Pittsburgh Amtrak Stationtrain train
    7h 19m
    $90–385

  8. Fly Chicago O'Hare International Airport to Morgantown Municipal Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Morgantown Municipal Airport (MGW)plane plane ORD - MGW
    2. Take the bus from Morgantown Mountaineer Station WVU to Pittsburgh Intermodal Stationbus bus
    6h 52m
    $80–354

Lisle to Pittsburgh by train (Amtrak)

Calendar7Weekly Trains
Duration11h 23mAverage Duration
Ticket$115Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Lisle to Pittsburgh.ExpandLaunch map view
  • Distance: 462.3 mi
  • Duration: 5h 35m

What companies run services between Lisle, IL, USA and Pittsburgh, PA, USA?

Amtrak operates a train from Chicago Union Station to Pittsburgh Amtrak Station once daily. Tickets cost $110–280 and the journey takes 9h 25m. Alternatively, Flixbus USA operates a bus from Chicago to Pittsburgh Intermodal Station 6 times a week. Tickets cost $75–120 and the journey takes 10h 35m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There