There are 6 ways to get from Lisse to Brussels by bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 361 bus, train
best- Take the bus from Lisse, Centrum to Schiphol, Airport/Plazabus 361
- Take the train from Schiphol Airport to Brussel-Zuid / Bruxelles-Miditrain Thalys
3h 6m€81–128Bus
cheapest- Take the bus from Amsterdam Schiphol Airport to Brussels-North train stationbus 817 / ...
5h 29m€24–36Drive 189.6 km
- Drive from Lisse to Brusselscar 189.6 km
2h 24m€41–58Fly
- Fly from Amsterdam Airport Schiphol (AMS) to Brussels Airport (BRU)plane AMS - BRU
2h 29m€138–302Train
- Take the train from Rotterdam Centraal to Brussels-Nordtrain Ec / ...
3h 50m€37–59Train via Roosendaal
- Take the train from Leiden Centraal to Roosendaaltrain Intercity
- Take the train from Roosendaal to Bruxelles-Centraltrain Ec
4h 2m€24–50
Lisse to Brussels by bus and train
Comparing Your Travel Options
The cheapest way to get from Lisse to Brussels is to bus which costs €24 - €40 and takes 5h 29m.
The fastest way to get from Lisse to Brussels is to drive which takes 2h 24m and costs €40 - €60.
No, there is no direct bus from Lisse to Brussels station. However, there are services departing from Lisse, Centrum and arriving at Brussels-North train station via Amsterdam Schiphol Airport. The journey, including transfers, takes approximately 5h 29m.
No, there is no direct train from Lisse to Brussels. However, there are services departing from Leiden Centraal and arriving at Brussels-Nord via Rotterdam Centraal. The journey, including transfers, takes approximately 3h 50m.
The distance between Lisse and Brussels is 215 km. The road distance is 189.6 km.
The best way to get from Lisse to Brussels without a car is to line 361 bus and train which takes 3h 6m and costs €80 - €130.
It takes approximately 3h 6m to get from Lisse to Brussels, including transfers.
Lisse to Brussels bus services, operated by FlixBus, depart from Amsterdam Schiphol Airport station.
Lisse to Brussels train services, operated by Belgian Railways (NMBS/SNCB), depart from Rotterdam Centraal station.
The best way to get from Lisse to Brussels is to bus which takes 5h 29m and costs €24 - €40. Alternatively, you can fly, which costs €130 - €310 and takes 2h 29m, you could also train, which costs €35 - €60 and takes 3h 50m.
What companies run services between Lisse, Netherlands and Brussels, Belgium?
FlixBus operates a bus from Amsterdam Schiphol Airport to Brussels-North train station every 2 hours. Tickets cost €18–28 and the journey takes 3h 55m. Alternatively, KLM flies from Amsterdam Airport Schiphol (AMS) to Brussels Airport (BRU) 4 times a day.
- Website
- klm.com
Flights from Amsterdam Airport Schiphol to Brussels Airport
- Ave. Duration
- 43 min
- When
- Every day
- Estimated price
- €40–310
- Phone
- +44 (0)3432 186 186
- Website
- Eurostar
Train from Schiphol Airport to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- €75–120
- Website
- Eurostar
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Rotterdam Centraal to Brussels-Nord
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €28–45
- Website
- Belgian Railways
Train from Roosendaal to Bruxelles-Central
- Ave. Duration
- 1h 28m
- Frequency
- Hourly
- Estimated price
- €16–25
- Website
- Belgian Railways
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Leiden Centraal to Roosendaal
- Ave. Duration
- 1h 19m
- Frequency
- Hourly
- Estimated price
- €10–19
- Website
- Nederlandse Spoorwegen (NS)
Train from Roosendaal to Bruxelles-Central
- Ave. Duration
- 1h 32m
- Frequency
- Every 4 hours
- Estimated price
- €9–18
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +31 900 0155
- Website
- Qbuzz B.V.
Bus from Lisse, Centrum to Schiphol, Airport/Plaza
- Ave. Duration
- 34 min
- Frequency
- Hourly
- Estimated price
- €6–8
- Website
- Qbuzz B.V.
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Amsterdam Schiphol Airport to Brussels-North train station
- Ave. Duration
- 3h 55m
- Frequency
- Every 2 hours
- Estimated price
- €18–28
- Website
- Flixbus
Want to know more about travelling around Belgium
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Related travel guides
Want to know more about Flixbus?
Read the travel guide
Booking & Getting There
Lisse to Brussels bus services, operated by FlixBus, arrive at Brussels-North train station.
Lisse to Brussels train services, operated by Belgian Railways (NMBS/SNCB), arrive at Brussels-Nord station.
Yes, the driving distance between Lisse to Brussels is 190 km. It takes approximately 2h 24m to drive from Lisse to Brussels.
There are 1700+ hotels available in Brussels.
























