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How to get fromLittle Rock to Murphysboroby bus, train, car, or plane

Find Transport to Murphysboro

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There are 5 ways to get from Little Rock to Murphysboro by bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Shell gas station - Little Rock, AR to Marathon Gas Station - Marionbus bus Milwaukee
    8h 27m
    $121–151

  2. Drive  327.7 mi

    cheapest
    1. Drive from Little Rock to Murphysborocar car 327.7 mi
    5h 47m
    $60–87

  3. Train, bus

    1. Take the train from Union Station to St. Louistrain train Texas Eagle
    2. Take the bus from St. Louis to Carbondalebus bus Amtrak Thruway Connecting Service
    10h 56m
    $223–337

  4. Fly to Williamson County Regional Airport

    1. Fly from Bill And Hillary Clinton National Airport (LIT) to Williamson County Regional Airport (MWA)plane plane LIT - MWA
    6h 35m
    $146–529

  5. Fly to Lambert–St. Louis International Airport, bus

    1. Fly from Bill And Hillary Clinton National Airport (LIT) to Lambert–St. Louis International Airport (STL)plane plane LIT - STL
    2. Take the bus from St. Louis to Carbondalebus bus
    7h 34m
    $138–558

Bill And Hillary Clinton National Airport (LIT) to Williamson County Regional Airport (MWA) flights

Calendar45Weekly Planes
Duration9h 13mAverage Duration
Ticket$87Cheapest Price
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Comparing Your Travel Options

Map of how to get from Little Rock to Murphysboro.ExpandLaunch map view
  • Distance: 382.7 mi
  • Duration: 8h 27m

What companies run services between Little Rock, AR, USA and Murphysboro, IL, USA?

Tornado Bus Company operates a bus from Shell gas station - Little Rock, AR to Marathon Gas Station - Marion once daily. Tickets cost $70–90 and the journey takes 6h 28m. Alternatively, American Airlines, United Airlines, and two other airlines fly from Bill And Hillary Clinton National Airport (LIT) to Williamson County Regional Airport (MWA) every 4 hours.

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