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How to get fromLong Island to Mayo Clinicby plane, train, bus, bus (Flixbus, Greyhound), car, or bus (Greyhound, Amtrak)

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There are 10 ways to get from Long Island to Mayo Clinic by plane, train, bus, bus (Flixbus, Greyhound), car, or bus (Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Laguardia Airport to Rochester

    best
    1. Fly from Laguardia Airport (LGA) to Rochester (RST)plane plane LGA - RST
    6h 25m
    $117–611

  2. Fly Newark Liberty International Airport to Rochester

    cheapest
    1. Fly from Newark Liberty International Airport (EWR) to Rochester (RST)plane plane EWR - RST
    8h 6m
    $116–542

  3. Train, bus via Madison

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    30h 38m
    $578–983

  4. Bus

    1. Take the bus from New York City Chinatown to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to Rochesterbus bus
    31h 49m
    $247–371

  5. Drive  1,140.8 mi

    1. Drive from Brooklyn to Mayo Cliniccar car 1,140.8 mi
    19h 2m
    $195–282

  6. Fly Laguardia Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Laguardia Airport (LGA) to Minneapolis–Saint Paul International Airport (MSP)plane plane LGA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 9m
    $198–780

  7. Fly John F. Kennedy International Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from John F. Kennedy International Airport (JFK) to Minneapolis–Saint Paul International Airport (MSP)plane plane JFK - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 22m
    $503–1,055

  8. Fly Newark Liberty International Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Newark Liberty International Airport (EWR) to Minneapolis–Saint Paul International Airport (MSP)plane plane EWR - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 4m
    $245–932

  9. Train, bus

    1. Take the train from Grand Central Terminal to Croton-Harmontrain train
    2. Take the train from Croton-Harmon Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochesterbus bus
    32h 20m
    $762–1,211

  10. Bus via Toledo

    1. Take the bus from Port Authority Bus Terminal to Toledo Bus Stopbus bus
    2. Take the bus from Toledo to Chicago Union Stationbus bus
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    32h 30m

Long Island to Mayo Clinic by subway, train, bus, and foot

Calendar7Weekly Services
Duration30h 38mAverage Duration
Ticket$578Cheapest Price
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Comparing Your Travel Options

Map of how to get from Long Island to Mayo Clinic.ExpandLaunch map view
  • Distance: 982.3 mi
  • Duration: 6h 25m

What companies run services between Long Island, Suffolk County, NY, USA and Mayo Clinic, MN, USA?

Delta and American Airlines fly from Laguardia Airport (LGA) to Rochester (RST) every 2 hours. Alternatively, you can take a bus from Cherry St/Jackson St to Mayo Clinic via Madison St/Pike St, New York City Chinatown, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 31h 49m.

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Want to know more about travelling around United States

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