There are 5 ways to get from Los Angeles Union Station to Otay Mesa by train, tram, bus (Greyhound), car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, tram
best- Take the train from Los Angeles to San Diego Old Town Transportation Centertrain Pacific Surfliner
- Take the tram from Old Town Station to Iris Avenue Stationtram Blue
4h 10m$42–97Bus via Old Town Station (Greyhound)
cheapest- Take the bus from Los Angeles Union Station to San Diego Greyhound Bus Stopbus Greyhound US0831
4h 53m$24–55Bus (Greyhound)
- Take the bus from Los Angeles Union Station to San Ysidrobus Los Angeles
4h 15m$30–53Drive 135.8 mi
- Drive from Los Angeles Union Station to Otay Mesacar 135.8 mi
2h 24m$25–36Fly, tram, line 905 bus
- Fly from Los Angeles International Airport (LAX) to San Diego International Airport (SAN)plane LAX - SAN
- Take the tram from Civic Center Station to Iris Avenue Stationtram
- Take the bus from Iris Avenue Transit Center to Otay Mesa Rd & Cactus Rdbus
4h 13m$174–587
Los Angeles Union Station to Otay Mesa by foot, train, tram, and bus
Questions & Answers
The cheapest way to get from Los Angeles Union Station to Otay Mesa is to drive which costs $24 - $40 and takes 2h 24m.
The fastest way to get from Los Angeles Union Station to Otay Mesa is to drive which takes 2h 24m and costs $24 - $40.
No, there is no direct bus from Los Angeles Union Station station to Otay Mesa. However, there are services departing from Los Angeles Union Station and arriving at Otay Mesa Rd & Cactus Rd via San Ysidro Bl & Virginia Av and Iris Avenue Transit Center. The journey, including transfers, takes approximately 4h 15m.
No, there is no direct train from Los Angeles Union Station to Otay Mesa station. However, there are services departing from Los Angeles and arriving at Iris Avenue Station via Old Town Station. The journey, including transfers, takes approximately 4h 10m.
The distance between Los Angeles Union Station and Otay Mesa is 146 miles. The road distance is 136.6 miles.
The best way to get from Los Angeles Union Station to Otay Mesa without a car is to train and tram which takes 4h 10m and costs $40 - $100.
It takes approximately 4h 10m to get from Los Angeles Union Station to Otay Mesa, including transfers.
Los Angeles Union Station to Otay Mesa bus services, operated by Greyhound Mexico, depart from Los Angeles Union Station.
Los Angeles Union Station to Otay Mesa train services, operated by Amtrak, depart from Los Angeles station.
Los Angeles Union Station to Otay Mesa bus services, operated by Greyhound Mexico, arrive at San Ysidro station.
What companies run services between Los Angeles Union Station, Los Angeles County, CA, USA and Otay Mesa, CA, USA?
Greyhound Mexico operates a bus from Los Angeles Union Station to San Ysidro 3 times a day. Tickets cost $26–45 and the journey takes 3h 30m.
- Website
- delta.com
Flights from Los Angeles International Airport to San Diego International Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- $30–260
- Website
- united.com
Flights from Los Angeles International Airport to San Diego International Airport
- Ave. Duration
- 57 min
- When
- Every day
- Estimated price
- $30–260
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Los Angeles to San Diego Old Town Transportation Center
- Ave. Duration
- 2h 42m
- Frequency
- Hourly
- Estimated price
- $35–85
- Website
- Amtrak
- Phone
- +1 619-557-4555
- Website
- MTS
Tram from Old Town Station to Iris Avenue Station
- Ave. Duration
- 50 min
- Frequency
- Every 20 minutes
- Estimated price
- $2–12
- Website
- MTS
- Schedules at
- MTS Schedules
Tram from Civic Center Station to Iris Avenue Station
- Ave. Duration
- 36 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–14
- Website
- MTS
- Schedules at
- MTS Schedules
- Phone
- +1-800-231-2222
- [email protected]
- Website
- Greyhound Mexico
Bus from Los Angeles Union Station to San Ysidro
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $26–45
- Schedules at
- Greyhound Mexico
- Phone
- +1 619-557-4555
- Website
- MTS
Bus from Iris Avenue Transit Center to Otay Mesa Rd & Cactus Rd
- Ave. Duration
- 11 min
- Frequency
- Every 30 minutes
- Estimated price
- $2–5
- Website
- MTS
- Schedules at
- MTS Schedules
- One Way - Adult/Youth
- $2–5
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Los Angeles Union Station to San Diego Greyhound Bus Stop
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $19–40
- Website
- Greyhound
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More Questions & Answers
Los Angeles Union Station to Otay Mesa train services, operated by Amtrak, arrive at San Diego Old Town Transportation Center station.
Yes, the driving distance between Los Angeles Union Station to Otay Mesa is 137 miles. It takes approximately 2h 24m to drive from Los Angeles Union Station to Otay Mesa.
There are 561+ hotels available in Otay Mesa.














