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How to get fromLos Angeles to Des Moinesby plane, bus (Greyhound), train, bus, or car

Find Transport to Des Moines

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There are 6 ways to get from Los Angeles to Des Moines by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Los Angeles International Airport

    best
    1. Fly from Los Angeles International Airport (LAX) to Des Moines (DSM)plane plane LAX - DSM
    5h 16m
    $136–396

  2. Fly from Burbank Bob Hope Airport

    cheapest
    1. Fly from Burbank Bob Hope Airport (BUR) to Des Moines (DSM)plane plane BUR - DSM
    6h 34m
    $125–492

  3. Bus (Greyhound)

    1. Take the bus from Los Angeles Union Station to Las Vegas Bus Terminalbus bus
    2. Take the bus from Las Vegas Bus Terminal to Denver Union Stationbus bus
    3. Take the bus from Denver Union Station to Des Moinesbus bus
    37h 5m
    $253–428

  4. Train, bus

    1. Take the train from Los Angeles to Kansas Citytrain train Southwest Chief
    2. Take the bus from Kansas City Bus Station to Des Moinesbus bus Greyhound US0156
    40h 4m
    $501–1,081

  5. Drive  1,682.1 mi

    1. Drive from Los Angeles to Des Moinescar car 1,682.1 mi
    26h 3m
    $307–444

  6. Line 43 bus to John Wayne Airport Orange County, fly

    1. Take the bus from Fullerton Trans Ctr Dock 1 to Harbor And Macarthurbus bus
    2. Fly from John Wayne Airport Orange County (SNA) to Des Moines (DSM)plane plane SNA - DSM
    7h 33m
    $138–591

Los Angeles to Des Moines by bus (Greyhound)

Calendar7Weekly Buses
Duration37h 5mAverage Duration
Ticket$253Cheapest Price
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Comparing Your Travel Options

Map of how to get from Los Angeles to Des Moines.ExpandLaunch map view
  • Distance: 1,465.7 mi
  • Duration: 5h 16m

What companies run services between Los Angeles, CA, USA and Des Moines, IA, USA?

American Airlines, Southwest Airlines, and three other airlines fly from Los Angeles International Airport (LAX) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from Los Angeles Union Station to Des Moines via Las Vegas Bus Terminal and Denver Union Station in around 37h 5m.

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Want to know more about travelling around United States

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Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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