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How to get fromLos Angeles to Des Moinesby plane, bus (Greyhound), train, bus, or car

Find Transport to Des Moines

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There are 8 ways to get from Los Angeles to Des Moines by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Los Angeles International Airport

    best
    1. Fly from Los Angeles International Airport (LAX) to Des Moines (DSM)plane plane LAX - DSM
    5h 22m
    $126–356

  2. Fly from Burbank Bob Hope Airport

    cheapest
    1. Fly from Burbank Bob Hope Airport (BUR) to Des Moines (DSM)plane plane BUR - DSM
    6h 36m
    $115–452

  3. Bus (Greyhound)

    1. Take the bus from Los Angeles Union Station to Las Vegas Bus Terminalbus bus
    2. Take the bus from Las Vegas Bus Terminal to Denver Union Stationbus bus
    3. Take the bus from Denver Union Station to Des Moinesbus bus
    37h 5m
    $275–439

  4. Train, bus

    1. Take the train from Los Angeles to Kansas Citytrain train Southwest Chief
    2. Take the bus from Kansas City Bus Station to Des Moinesbus bus Greyhound US0156
    40h 4m
    $522–1,294

  5. Drive  1,682.1 mi

    1. Drive from Los Angeles to Des Moinescar car 1,682.1 mi
    26h 3m
    $307–444

  6. Train to Ontario International Airport, fly

    1. Take the train from Los Angeles to Ontario Amtraktrain train
    2. Fly from Ontario International Airport (ONT) to Des Moines (DSM)plane plane ONT - DSM
    7h 16m
    $150–441

  7. Line 43 bus to John Wayne Airport Orange County, fly

    1. Take the bus from Fullerton Trans Ctr Dock 1 to Harbor And Macarthurbus bus
    2. Fly from John Wayne Airport Orange County (SNA) to Des Moines (DSM)plane plane SNA - DSM
    7h 33m
    $149–424

  8. Fly from Long Beach Airport

    1. Fly from Long Beach Airport (LGB) to Des Moines (DSM)plane plane LGB - DSM
    8h 15m
    $174–729

Los Angeles to Des Moines by bus (Greyhound)

Calendar7Weekly Buses
Duration37h 5mAverage Duration
Ticket$275Cheapest Price
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Comparing Your Travel Options

Map of how to get from Los Angeles to Des Moines.ExpandLaunch map view
  • Distance: 1,465.7 mi
  • Duration: 5h 22m

What companies run services between Los Angeles, CA, USA and Des Moines, IA, USA?

American Airlines, Southwest Airlines, and three other airlines fly from Los Angeles International Airport (LAX) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from Los Angeles Union Station to Des Moines via Las Vegas Bus Terminal and Denver Union Station in around 37h 5m.

Airlines
Train operators
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Need to know: Greyhound

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