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How to get fromLos Angeles to Florenceby plane, train, bus, bus (Greyhound, Flixbus), car, or train (Amtrak)

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There are 6 ways to get from Los Angeles to Florence by plane, train, bus, bus (Greyhound, Flixbus), car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Los Angeles International Airport

    best
    1. Fly from Los Angeles International Airport (LAX) to Florence Regional Airport (FLO)plane plane LAX - FLO
    10h 18m
    $178–676

  2. Train, bus

    1. Take the train from Los Angeles to Houstontrain train
    2. Take the bus from Houston - Harrisburg Blvd to Atlantabus bus
    3. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus
    2d 10h
    $703–1,334

  3. Bus

    1. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus
    2d 12h
    $419–808

  4. Drive 2,446.7 mi

    1. Drive from Los Angeles to Florencecar car 2,446.7 mi
    39h
    $447–645

  5. Train to Ontario International Airport, fly

    1. Take the train from Los Angeles to Ontario Amtraktrain train
    2. Fly from Ontario International Airport (ONT) to Florence Regional Airport (FLO)plane plane ONT - FLO
    11h 23m
    $204–790

  6. Train (Amtrak)

    1. Take the train from Los Angeles to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Selma Stationtrain train
    4. Take the train from Selma Station to Florence Stationtrain train
    3d 1h
    $1,109–2,327

Los Angeles to Florence by bus

Calendar7Weekly Buses
Duration2d 12hAverage Duration
Ticket$419Cheapest Price
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Questions & Answers

Map of how to get from Los Angeles to Florence.ExpandLaunch map view
  • Distance: 2,217.2 mi
  • Duration: 10h 18m

What companies run services between Los Angeles, CA, USA and Florence, SC, USA?

American Airlines and Southwest Airlines fly from Los Angeles International Airport (LAX) to Florence Regional Airport (FLO) 5 times a day. Alternatively, you can take a bus from Los Angeles Union Station to Florence Bus Station via St Louis Bus Station and Atlanta Bus Station in around 2d 12h.

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Bus operators

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