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How to get fromLos Angeles to Knoxvilleby plane, train, bus, bus (Greyhound), or car

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There are 11 ways to get from Los Angeles to Knoxville by plane, train, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Los Angeles International Airport to Mcghee Tyson Airport

    best
    1. Fly from Los Angeles International Airport (LAX) to Mcghee Tyson Airport (TYS)plane plane LAX - TYS
    8h 13m
    $323–1,183

  2. Fly Los Angeles International Airport to Nashville, drive

    cheapest
    1. Fly from Los Angeles International Airport (LAX) to Nashville (BNA)plane plane LAX - BNA
    2. Drive from Nashville-Airport-BNA to Knoxvillecar car
    8h 24m
    $228–383

  3. Train, bus

    1. Take the train from Los Angeles to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus
    3d 6h
    $1,222–2,374

  4. Bus

    1. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus
    3d 7h
    $636–1,115

  5. Drive 2,166.3 mi

    1. Drive from Los Angeles to Knoxvillecar car 2,166.3 mi
    34h 17m
    $396–572

  6. Fly Burbank Bob Hope Airport to Mcghee Tyson Airport

    1. Fly from Burbank Bob Hope Airport (BUR) to Mcghee Tyson Airport (TYS)plane plane BUR - TYS
    7h 44m
    $332–1,179

  7. Train to Ontario International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Los Angeles to Ontario Amtraktrain train
    2. Fly from Ontario International Airport (ONT) to Mcghee Tyson Airport (TYS)plane plane ONT - TYS
    8h 38m
    $359–1,047

  8. Fly Long Beach Airport to Mcghee Tyson Airport

    1. Fly from Long Beach Airport (LGB) to Mcghee Tyson Airport (TYS)plane plane LGB - TYS
    9h 25m
    $341–1,276

  9. Fly Burbank Bob Hope Airport to Nashville, drive

    1. Fly from Burbank Bob Hope Airport (BUR) to Nashville (BNA)plane plane BUR - BNA
    2. Drive from Nashville-Airport-BNA to Knoxvillecar car
    8h 27m
    $247–759

  10. Fly John Wayne Airport Orange County to Mcghee Tyson Airport

    1. Fly from John Wayne Airport Orange County (SNA) to Mcghee Tyson Airport (TYS)plane plane SNA - TYS
    10h 26m
    $347–990

  11. Train, bus via Anaheim

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus
    3d 7h
    $1,156–2,329

Los Angeles International Airport (LAX) to Mcghee Tyson Airport (TYS) flights

Calendar70Weekly Planes
Duration7h 6mAverage Duration
Ticket$260Cheapest Price
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Questions & Answers

Map of how to get from Los Angeles to Knoxville.ExpandLaunch map view
  • Distance: 1,972.5 mi
  • Duration: 8h 13m

What companies run services between Los Angeles, CA, USA and Knoxville, TN, USA?

Delta, American Airlines, and Southwest Airlines fly from Los Angeles International Airport (LAX) to Mcghee Tyson Airport (TYS) every 3 hours. Alternatively, you can take a bus from Los Angeles Union Station to Knoxville via St Louis Bus Station, Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 3d 7h.

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