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How to get fromLos Angeles to Mayo Clinicby plane, bus (Greyhound), train, bus, or car

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There are 8 ways to get from Los Angeles to Mayo Clinic by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Los Angeles International Airport to Rochester

    best
    1. Fly from Los Angeles International Airport (LAX) to Rochester (RST)plane plane LAX - RST
    8h
    $129–603

  2. Bus

    1. Take the bus from Los Angeles Union Station to Tulsa Bus Stationbus bus
    2. Take the bus from Tulsa to St. Paulbus bus
    3. Take the bus from St. Paul to Rochester, MNbus bus
    2d 2h
    $409–696

  3. Train, bus

    1. Take the train from Los Angeles to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    2d 5h
    $799–1,600

  4. Drive 1,842.7 mi

    1. Drive from Los Angeles to Mayo Cliniccar car 1,842.7 mi
    29h 56m
    $337–486

  5. Fly Los Angeles International Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Los Angeles International Airport (LAX) to Minneapolis–Saint Paul International Airport (MSP)plane plane LAX - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 57m
    $180–475

  6. Fly Burbank Bob Hope Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Burbank Bob Hope Airport (BUR) to Minneapolis–Saint Paul International Airport (MSP)plane plane BUR - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 35m
    $209–761

  7. Fly John Wayne Airport Orange County to Rochester

    1. Fly from John Wayne Airport Orange County (SNA) to Rochester (RST)plane plane SNA - RST
    11h 16m
    $143–660

  8. Fly John Wayne Airport Orange County to Minneapolis–Saint Paul International Airport, bus

    1. Fly from John Wayne Airport Orange County (SNA) to Minneapolis–Saint Paul International Airport (MSP)plane plane SNA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    10h 39m
    $404–542

Los Angeles to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration2d 2hAverage Duration
Ticket$409Cheapest Price
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Questions & Answers

Map of how to get from Los Angeles to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,569 mi
  • Duration: 8h

What companies run services between Los Angeles, CA, USA and Mayo Clinic, MN, USA?

Delta, American Airlines, and United Airlines fly from Los Angeles International Airport (LAX) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Los Angeles Union Station to Mayo Clinic via Tulsa, St. Paul, and Rochester in around 2d 2h.

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