There are 10 ways to get from Los Angeles to Mesquite by bus, car, plane, shuttle, bus (Flixbus), or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Downtown Los Angeles to Las Vegasbus San Ysidro
- Take the bus from Las Vegas to Mesquite, NVbus Las Vegas
7h 10m$93–141Drive 348 mi
cheapest- Drive from Los Angeles to Mesquitecar 348 mi
5h 37m$64–92Fly Los Angeles International Airport to Harry Reid International Airport, shuttle
- Fly from Los Angeles International Airport (LAX) to Harry Reid International Airport (LAS)plane LAX - LAS
- Take a shuttle bus from Harry Reid International to Mesquite, NV - Eureka Casino
4h 59m$138–858Bus via Las Vegas
- Take the bus from Los Angeles Downtown to Las Vegas Downtownbus FlixBus 2030
- Take the bus from Harry Reid International to Mesquite, NVbus Las Vegas
8h 51m$67–126Fly Burbank Bob Hope Airport to Harry Reid International Airport, shuttle
- Fly from Burbank Bob Hope Airport (BUR) to Harry Reid International Airport (LAS)plane BUR - LAS
- Take a shuttle bus from Harry Reid International to Mesquite, NV - Eureka Casino
4h 58m$187–954Train to Ontario International Airport, fly to Harry Reid International Airport, shuttle
- Take the train from Los Angeles to Ontario Amtraktrain
- Fly from Ontario International Airport (ONT) to Harry Reid International Airport (LAS)plane ONT - LAS
- Take a shuttle bus from Harry Reid International to Mesquite, NV - Eureka Casino
5h 40m$214–531Fly Santa Monica to Harry Reid International Airport, shuttle
- Fly from Santa Monica (SMO) to Harry Reid International Airport (LAS)plane SMO - LAS
- Take a shuttle bus from Harry Reid International to Mesquite, NV - Eureka Casino
5h 41m$73–328Fly Long Beach Airport to Harry Reid International Airport, shuttle
- Fly from Long Beach Airport (LGB) to Harry Reid International Airport (LAS)plane LGB - LAS
- Take a shuttle bus from Harry Reid International to Mesquite, NV - Eureka Casino
6h 38m$76–331Fly Los Angeles International Airport to St. George Regional, bus
- Fly from Los Angeles International Airport (LAX) to St. George Regional (SGU)plane LAX - SGU
- Take the bus from Utah Tech - St George to Mesquite, NVbus
6h 39m$92–388Line 43 bus to John Wayne Airport Orange County, fly to Harry Reid International Airport, shuttle
- Take the bus from Fullerton Trans Ctr Dock 1 to Harbor And Macarthurbus
- Fly from John Wayne Airport Orange County (SNA) to Harry Reid International Airport (LAS)plane SNA - LAS
- Take a shuttle bus from Harry Reid International to Mesquite, NV - Eureka Casino
7h 32m$142–535
Los Angeles to Mesquite by bus
Questions & Answers
The cheapest way to get from Los Angeles to Mesquite is to drive which costs $60 - $95 and takes 5h 37m.
The fastest way to get from Los Angeles to Mesquite is to fly and shuttle which takes 4h 58m and costs $180 - $1,000.
No, there is no direct bus from Los Angeles to Mesquite. However, there are services departing from Downtown Los Angeles and arriving at Mesquite, NV via Las Vegas. The journey, including transfers, takes approximately 7h 10m.
The distance between Los Angeles and Mesquite is 371 miles. The road distance is 350.1 miles.
The best way to get from Los Angeles to Mesquite without a car is to bus which takes 7h 10m and costs $90 - $150.
It takes approximately 7h 10m to get from Los Angeles to Mesquite, including transfers.
Los Angeles to Mesquite bus services, operated by Flixbus USA, depart from Los Angeles Downtown station.
Los Angeles to Mesquite bus services, operated by Flixbus USA, arrive at Las Vegas Downtown station.
Yes, the driving distance between Los Angeles to Mesquite is 350 miles. It takes approximately 5h 37m to drive from Los Angeles to Mesquite.
Book your Los Angeles to Mesquite bus tickets online with Omio.
What companies run services between Los Angeles, CA, USA and Mesquite, NV, USA?
You can take a bus from Downtown Los Angeles to Mesquite, NV via Las Vegas in around 7h 10m.
- Website
- southwest.com
Flights from Los Angeles International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $35–260
Flights from Burbank Bob Hope Airport to Harry Reid International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $35–260
Flights from Ontario International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $40–280
Flights from Long Beach Airport to Harry Reid International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $40–280
Flights from John Wayne Airport Orange County to Harry Reid International Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $40–280
- Website
- jsx.com
Flights from Los Angeles International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $35–260
Flights from Burbank Bob Hope Airport to Harry Reid International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $35–260
Flights from Santa Monica to Harry Reid International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $40–280
Flights from John Wayne Airport Orange County to Harry Reid International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $40–280
- Website
- united.com
Flights from Los Angeles International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $35–260
Flights from Los Angeles International Airport to St. George Regional
- Ave. Duration
- 1h 40m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $45–290
- Website
- delta.com
Flights from Los Angeles International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $35–260
Flights from Los Angeles International Airport to St. George Regional via Salt Lake City
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $75–390
Flights from John Wayne Airport Orange County to Harry Reid International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $40–280
- Website
- flyfrontier.com
Flights from Los Angeles International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $85–190
Flights from Burbank Bob Hope Airport to Harry Reid International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $35–200
Flights from Ontario International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $170–440
Flights from John Wayne Airport Orange County to Harry Reid International Airport
- Ave. Duration
- 1h 11m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–230
- Website
- aa.com
Flights from Los Angeles International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $35–260
- Website
- flybreeze.com
Flights from John Wayne Airport Orange County to Harry Reid International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $110–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Los Angeles to Ontario Amtrak
- Ave. Duration
- 54 min
- Frequency
- 6 times a week
- Estimated price
- $11–25
- Website
- Amtrak
- Phone
- +1 833 766 3553
- Website
- Tufesa
Bus from Downtown Los Angeles to Las Vegas
- Ave. Duration
- 5h
- Frequency
- Twice daily
- Estimated price
- $60–90
- Schedules at
- Tufesa
- Adult One way
- $60–90
Bus from Las Vegas to Mesquite, NV
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $30–55
- Schedules at
- Tufesa
- Adult One way
- $30–55
- Phone
- +1 800-933-8320
- [email protected]
- Website
- St. George Shuttle
Shuttle from Harry Reid International to Mesquite, NV - Eureka Casino
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $30–45
- Website
- St. George Shuttle
Shuttle from Harry Reid International to Mesquite, NV - Eureka Casino
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $30–45
- Website
- St. George Shuttle
Shuttle from Harry Reid International to Mesquite, NV - Eureka Casino
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $30–45
- Website
- St. George Shuttle
Shuttle from Harry Reid International to Mesquite, NV - Eureka Casino
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $30–45
- Website
- St. George Shuttle
Shuttle from Harry Reid International to Mesquite, NV - Eureka Casino
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $30–45
- Website
- St. George Shuttle
Shuttle from Harry Reid International to Mesquite, NV - Eureka Casino
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $30–45
- Website
- St. George Shuttle
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Los Angeles Downtown to Las Vegas Downtown
- Ave. Duration
- 5h 35m
- Frequency
- 3 times a day
- Estimated price
- $40–70
- Schedules at
- Flixbus USA
- Phone
- +1 208-656-8824
- [email protected]
- Website
- Salt Lake Express
Bus from Harry Reid International to Mesquite, NV
- Ave. Duration
- 1h 26m
- Frequency
- Every 3 hours
- Estimated price
- $22–55
- Website
- Salt Lake Express
Bus from Utah Tech - St George to Mesquite, NV
- Ave. Duration
- 45 min
- Frequency
- Every 4 hours
- Estimated price
- $15–50
- Website
- Salt Lake Express
- Phone
- +1 714-560-6282
- Website
- octa.net
Bus from Fullerton Trans Ctr Dock 1 to Harbor And Macarthur
- Ave. Duration
- 1h 7m
- Frequency
- Every 15 minutes
- Estimated price
- $1–2
- Schedules at
- octa.net
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 42+ hotels available in Mesquite.

















