There are 3 ways to get from Los Osos to San Diego by bus, plane, train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, fly
best- Take the bus from 10th & Los Osos Valley to Government Centerbus
- Fly from San Luis Obispo County Regional Airport (SBP) to San Diego International Airport (SAN)plane SBP - SAN
4h 27m$173–355Drive 315.3 mi
cheapest- Drive from Los Osos to San Diegocar 315.3 mi
5h 41m$58–84Train (Amtrak)
- Take the train from San Luis Obispo to San Diegotrain Pacific Surfliner
9h 13m$152–280
San Luis Obispo County Regional Airport (SBP) to San Diego International Airport (SAN) flights
Questions & Answers
The cheapest way to get from Los Osos to San Diego is to drive which costs $55 - $85 and takes 5h 41m.
The fastest way to get from Los Osos to San Diego is to bus and fly which takes 4h 27m and costs $170 - $360.
No, there is no direct train from Los Osos to San Diego. However, there are services departing from San Luis Obispo and arriving at San Diego via . The journey, including transfers, takes approximately 9h 13m.
The distance between Los Osos and San Diego is 292 miles. The road distance is 317.1 miles.
The best way to get from Los Osos to San Diego without a car is to train which takes 9h 13m and costs $150 - $280.
It takes approximately 4h 27m to get from Los Osos to San Diego, including transfers.
Los Osos to San Diego train services, operated by Amtrak, depart from San Luis Obispo station.
Los Osos to San Diego train services, operated by Amtrak, arrive at San Diego station.
Yes, the driving distance between Los Osos to San Diego is 317 miles. It takes approximately 5h 41m to drive from Los Osos to San Diego.
Book your Los Osos to San Diego train tickets online with Omio.
What companies run services between Los Osos, CA, USA and San Diego, CA, USA?
Amtrak operates a train from San Luis Obispo to San Diego 3 times a day. Tickets cost $110–230 and the journey takes 8h 55m.
- Website
- alaskaair.com
Flights from San Luis Obispo County Regional Airport to San Diego International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $170–350
- Website
- united.com
Flights from San Luis Obispo County Regional Airport to San Diego International Airport via Los Angeles
- Ave. Duration
- 3h 28m
- When
- Saturday, Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $35–240
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Luis Obispo to San Diego
- Ave. Duration
- 8h 55m
- Frequency
- 3 times a day
- Estimated price
- $110–230
- Website
- Amtrak
.jpg "Pacific Surfliner interior")
- Website
- SoCoTransit
Bus from 10th & Los Osos Valley to Government Center
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- $2–3
- Website
- SoCoTransit
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