Rome2Rio

How to get fromLoudon to Des Moinesby taxi, plane, bus (Greyhound, Flixbus), car, bus (Flixbus, Amtrak, Greyhound), bus, train, or bus (Greyhound)

Find Transport to Des Moines

See all options

There are 8 ways to get from Loudon to Des Moines by taxi, plane, bus (Greyhound, Flixbus), car, bus (Flixbus, Amtrak, Greyhound), bus, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Mcghee Tyson Airport, fly

    best
    1. Take the taxi from Loudon to Mcghee Tyson Airport (TYS)taxi taxi
    2. Fly from Mcghee Tyson Airport (TYS) to Des Moines (DSM)plane plane TYS - DSM
    5h 5m
    $332–1,169

  2. Drive 799.5 mi

    cheapest
    1. Drive from Loudon to Des Moinescar car 799.5 mi
    14h 28m
    $146–211

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Central 5Th Ave - Bay 11 to Clarksville Exit 11 Park And Ridebus bus 94
    3. Take the bus from Clarksville Park & Ride to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Des Moinesbus bus
    21h 40m
    $210–342

  4. Drive to Chattanooga Metropolitan Airport, fly

    1. Drive from Loudon to Chattanooga Metropolitan Airport (CHA)car car
    2. Fly from Chattanooga Metropolitan Airport (CHA) to Des Moines (DSM)plane plane CHA - DSM
    5h 57m
    $261–1,241

  5. Drive to Asheville Regional Airport, fly

    1. Drive from Loudon to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Des Moines (DSM)plane plane AVL - DSM
    7h 19m
    $185–761

  6. Bus via Carbondale

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Central 5Th Ave - Bay 11 to Clarksville Exit 11 Park And Ridebus bus 94
    3. Take the bus from Clarksville Park & Ride to Carbondale Intermodal Stationbus bus
    4. Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus bus
    5. Take the bus from St Louis Bus Station to Des Moinesbus bus
    22h 5m
    $211–352

  7. Bus, train

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Kansas Citytrain train
    4. Take the bus from Kansas City Bus Station to Des Moinesbus bus
    24h 56m
    $305–538

  8. Bus via Indianapolis

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    26h 49m
    $268–495

Mcghee Tyson Airport (TYS) to Des Moines (DSM) flights

Calendar89Weekly Planes
Duration5h 12mAverage Duration
Ticket$194Cheapest Price
See schedules

Questions & Answers

Map of how to get from Loudon to Des Moines.ExpandLaunch map view
  • Distance: 687.8 mi
  • Duration: 5h 5m

What companies run services between Loudon, TN, USA and Des Moines, IA, USA?

You can take a vehicle from Loudon to Des Moines via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 5Th Ave - Bay 11, Clarksville Exit 11 Park And Ride, Clarksville Park & Ride, and St Louis Bus Station in around 21h 40m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers