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How to get fromLouisiana to Knoxvilleby plane, train, bus, shuttle, or car

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There are 5 ways to get from Louisiana to Knoxville by plane, train, bus, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Louis Armstrong New Orleans International Airport

    best
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Mcghee Tyson Airport (TYS)plane plane MSY - TYS
    3h 37m
    $204–864

  2. Drive 598.2 mi

    cheapest
    1. Drive from New Orleans to Knoxvillecar car 598.2 mi
    9h 46m
    $110–158

  3. Train, bus, shuttle, drive

    1. Take the train from New Orleans Union Passenger Terminal to Charlotte Amtrak Stationtrain train
    2. Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus bus
    3. Take a shuttle bus from Boone to Black Bear Resortshuttle bus
    4. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    5. Drive from Hot Springs to Knoxvillecar car
    28h 44m
    $583–870

  4. Fly from Lafayette Regional Airport

    1. Fly from Lafayette Regional Airport (LFT) to Mcghee Tyson Airport (TYS)plane plane LFT - TYS
    4h 28m
    $186–783

  5. Fly from Shreveport

    1. Fly from Shreveport (SHV) to Mcghee Tyson Airport (TYS)plane plane SHV - TYS
    5h 57m
    $189–749

Louis Armstrong New Orleans International Airport (MSY) to Mcghee Tyson Airport (TYS) flights

Calendar65Weekly Planes
Duration4hAverage Duration
Ticket$148Cheapest Price
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Questions & Answers

Map of how to get from Louisiana to Knoxville.ExpandLaunch map view
  • Distance: 554.7 mi
  • Duration: 3h 37m

What companies run services between Louisiana, USA and Knoxville, TN, USA?

Southwest Airlines, Delta, and American Airlines fly from Louis Armstrong New Orleans International Airport (MSY) to Mcghee Tyson Airport (TYS) every 3 hours.

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