There are 7 ways to get from Louisiana to San Antonio by plane, bus (Flixbus), train (Amtrak), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Louis Armstrong New Orleans International Airport
best- Fly from Louis Armstrong New Orleans International Airport (MSY) to San Antonio International Airport (SAT)plane MSY - SAT
2h 21m$106–580Fly from Lake Charles Regional Airport
cheapest- Fly from Lake Charles Regional Airport (LCH) to San Antonio International Airport (SAT)plane LCH - SAT
4h 2m$78–435Bus (Flixbus)
- Take the bus from New Orleans Bus Station to San Antonio Bus Stationbus FlixBus 2212
10h 5m$85–150Train (Amtrak)
- Take the train from New Orleans Union Passenger Terminal to San Antonio Stationtrain Sunset Limited
15h 5m$180–380Drive 540.9 mi
- Drive from New Orleans to San Antoniocar 540.9 mi
8h 54m$99–143Fly from Lafayette Regional Airport
- Fly from Lafayette Regional Airport (LFT) to San Antonio International Airport (SAT)plane LFT - SAT
4h 27m$83–455Bus via Houston
- Take the bus from New Orleans Bus Station to Houston Bus Stationbus Greyhound US0602
- Take the bus from Hyatt Regency Galleria Houston to San Antoniobus Houston
12h 18m$185–254
Louisiana to San Antonio by bus (Flixbus)
Questions & Answers
The cheapest way to get from Louisiana to San Antonio is to bus which costs $85 - $150 and takes 10h 5m.
The fastest way to get from Louisiana to San Antonio is to fly which takes 2h 21m and costs $100 - $600.
Yes, there is a direct bus departing from New Orleans Bus Station station and arriving at San Antonio Bus Station station. Services depart once daily, and operate Monday, Tuesday, Friday, Saturday and Sunday. The journey takes approximately 10h 5m.
Yes, there is a direct train departing from New Orleans Union Passenger Terminal and arriving at San Antonio Station station. Services depart three times a week, and operate Monday, Wednesday and Saturday. The journey takes approximately 15h 5m.
The distance between Louisiana and San Antonio is 505 miles. The road distance is 544.1 miles.
The best way to get from Louisiana to San Antonio without a car is to bus which takes 10h 5m and costs $85 - $150.
It takes approximately 2h 21m to get from Louisiana to San Antonio, including transfers.
Louisiana to San Antonio bus services, operated by Flixbus USA, depart from New Orleans Bus Station.
Louisiana to San Antonio train services, operated by Amtrak, depart from New Orleans Union Passenger Terminal station.
The best way to get from Louisiana to San Antonio is to fly which takes 2h 21m and costs $100 - $600. Alternatively, you can bus, which costs $85 - $150 and takes 10h 5m, you could also train, which costs $180 - $380 and takes 15h 5m.
What companies run services between Louisiana, USA and San Antonio, TX, USA?
Southwest Airlines, United Airlines, and American Airlines fly from Louis Armstrong New Orleans International Airport (MSY) to San Antonio International Airport (SAT) every 4 hours. Alternatively, Flixbus USA operates a bus from New Orleans Bus Station to San Antonio Bus Station once daily. Tickets cost $85–150 and the journey takes 10h 5m.
- Website
- united.com
Flights from Louis Armstrong New Orleans International Airport to San Antonio International Airport via Houston
- Ave. Duration
- 3h 36m
- When
- Every day
- Estimated price
- $100–600
Flights from Lake Charles Regional Airport to San Antonio International Airport via Houston
- Ave. Duration
- 3h 12m
- When
- Monday, Wednesday, Thursday, Friday, Sunday, and Tuesday
- Estimated price
- $65–420
Flights from Lafayette Regional Airport to San Antonio International Airport via Houston
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $70–440
- Website
- aa.com
Flights from Louis Armstrong New Orleans International Airport to San Antonio International Airport via Dallas/Ft.Worth
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $120–650
Flights from Lake Charles Regional Airport to San Antonio International Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $85–480
Flights from Lafayette Regional Airport to San Antonio International Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $90–490
- Website
- southwest.com
Flights from Louis Armstrong New Orleans International Airport to San Antonio International Airport
- Ave. Duration
- 1h 35m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $100–600
Flights from Louis Armstrong New Orleans International Airport to San Antonio International Airport via Houston Hobby Apt
- Ave. Duration
- 3h 35m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Flights from Louis Armstrong New Orleans International Airport to San Antonio International Airport via Dallas
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $120–650
- Website
- delta.com
Flights from Lafayette Regional Airport to San Antonio International Airport via Atlanta
- Ave. Duration
- 6h 56m
- When
- Every day
- Estimated price
- $160–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to San Antonio Station
- Ave. Duration
- 15h 5m
- Frequency
- 3 times a week
- Estimated price
- $180–380
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from New Orleans Bus Station to San Antonio Bus Station
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $85–150
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from New Orleans Bus Station to Houston Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- Every 4 hours
- Estimated price
- $50–110
- Website
- Greyhound
- Phone
- +1 844-866-5263
- [email protected]
- Website
- Vonlane
Bus from Hyatt Regency Galleria Houston to San Antonio
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $137–147
- Website
- Vonlane
- low
- $137
- high
- $147
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Louisiana to San Antonio bus services, operated by Flixbus USA, arrive at San Antonio Bus Station.
Louisiana to San Antonio train services, operated by Amtrak, arrive at San Antonio Station.
Yes, the driving distance between Louisiana to San Antonio is 544 miles. It takes approximately 8h 54m to drive from Louisiana to San Antonio.
Book your Louisiana to San Antonio train tickets online with Omio.
Book your Louisiana to San Antonio bus tickets online with Omio and FlixBus.
There are 1120+ hotels available in San Antonio.












