There are 6 ways to get from Louisiana to St. Louis by plane, bus (Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Louis Armstrong New Orleans International Airport
best- Fly from Louis Armstrong New Orleans International Airport (MSY) to Lambert–St. Louis International Airport (STL)plane MSY - STL
2h 28m$132–712Fly from Lake Charles Regional Airport
cheapest- Fly from Lake Charles Regional Airport (LCH) to Lambert–St. Louis International Airport (STL)plane LCH - STL
5h 2m$114–616Bus (Greyhound)
- Take the bus from New Orleans Bus Station to St Louis Bus Stationbus Greyhound US1173
14h 40m$130–200Train, bus
- Take the train from New Orleans Union Passenger Terminal to Carbondaletrain City of New Orleans
- Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus FlixBus N2521
16h 23m$358–550Drive 676.1 mi
- Drive from New Orleans to St. Louiscar 676.1 mi
10h 58m$120–173Fly from Lafayette Regional Airport
- Fly from Lafayette Regional Airport (LFT) to Lambert–St. Louis International Airport (STL)plane LFT - STL
5h 22m$124–616
Louisiana to St. Louis by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Louisiana to St. Louis is to drive which costs $110 - $180 and takes 10h 58m.
The fastest way to get from Louisiana to St. Louis is to fly which takes 2h 28m and costs $130 - $750.
Yes, there is a direct bus departing from New Orleans Bus Station station and arriving at St Louis Bus Station station. Services depart once daily, and operate every day. The journey takes approximately 14h 40m.
The distance between Louisiana and St. Louis is 623 miles. The road distance is 680 miles.
The best way to get from Louisiana to St. Louis without a car is to bus which takes 14h 40m and costs $130 - $200.
It takes approximately 2h 28m to get from Louisiana to St. Louis, including transfers.
Louisiana to St. Louis bus services, operated by Greyhound USA, depart from New Orleans Bus Station.
The best way to get from Louisiana to St. Louis is to fly which takes 2h 28m and costs $130 - $750. Alternatively, you can bus, which costs $130 - $200 and takes 14h 40m.
Louisiana to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Yes, the driving distance between Louisiana to St. Louis is 680 miles. It takes approximately 10h 58m to drive from Louisiana to St. Louis.
What companies run services between Louisiana, USA and St. Louis, MO, USA?
Southwest Airlines, Delta, and United Airlines fly from Louis Armstrong New Orleans International Airport (MSY) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, Greyhound USA operates a bus from New Orleans Bus Station to St Louis Bus Station once daily. Tickets cost $130–200 and the journey takes 14h 40m.
- Website
- southwest.com
Flights from Louis Armstrong New Orleans International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $120–750
Flights from Louis Armstrong New Orleans International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 3h 58m
- When
- Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $140–800
Flights from Louis Armstrong New Orleans International Airport to Lambert–St. Louis International Airport via Dallas
- Ave. Duration
- 4h 12m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $170–850
Flights from Louis Armstrong New Orleans International Airport to Lambert–St. Louis International Airport via Houston Hobby Apt
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $170–850
- Website
- united.com
Flights from Louis Armstrong New Orleans International Airport to Lambert–St. Louis International Airport via Houston
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $170–850
Flights from Lafayette Regional Airport to Lambert–St. Louis International Airport via Houston
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $110–600
Flights from Lake Charles Regional Airport to Lambert–St. Louis International Airport via Houston
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $100–600
- Website
- aa.com
Flights from Lafayette Regional Airport to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $110–600
Flights from Lafayette Regional Airport to Lambert–St. Louis International Airport via Charlotte
- Ave. Duration
- 8h 52m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $150–700
Flights from Lake Charles Regional Airport to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 54m
- When
- Every day
- Estimated price
- $110–600
- Website
- delta.com
Flights from Louis Armstrong New Orleans International Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $160–850
Flights from Lafayette Regional Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $120–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Carbondale
- Ave. Duration
- 13h 28m
- Frequency
- Once daily
- Estimated price
- $340–550
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from New Orleans Bus Station to St Louis Bus Station
- Ave. Duration
- 14h 40m
- Frequency
- Once daily
- Estimated price
- $130–200
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Carbondale Intermodal Station to St Louis Bus Station
- Ave. Duration
- 1h 55m
- Frequency
- 5 times a week
- Estimated price
- $15–23
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Carbondale Intermodal Station to St Louis Bus Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Website
- Amtrak
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Booking & Getting There
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