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How to get fromLouisiana to St. Louisby plane, bus (Greyhound), train, bus, or car

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There are 6 ways to get from Louisiana to St. Louis by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Louis Armstrong New Orleans International Airport

    best
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Lambert–St. Louis International Airport (STL)plane plane MSY - STL
    2h 28m
    $404–857

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from New Orleans Bus Station to St Louis Bus Stationbus bus Greyhound US1173
    14h 40m
    $110–220

  3. Train, bus

    1. Take the train from New Orleans Union Passenger Terminal to Carbondaletrain train City of New Orleans
    2. Take the bus from Carbondale to St. Louisbus bus Amtrak Thruway Connecting Service
    16h 28m
    $220–460

  4. Drive 676.1 mi

    1. Drive from New Orleans to St. Louiscar car 676.1 mi
    10h 58m
    $124–179

  5. Fly from Lake Charles Regional Airport

    1. Fly from Lake Charles Regional Airport (LCH) to Lambert–St. Louis International Airport (STL)plane plane LCH - STL
    5h 5m
    $134–616

  6. Fly from Lafayette Regional Airport

    1. Fly from Lafayette Regional Airport (LFT) to Lambert–St. Louis International Airport (STL)plane plane LFT - STL
    5h 13m
    $134–616

Louisiana to St. Louis by bus (Greyhound)

Calendar7Weekly Buses
Duration14h 40mAverage Duration
Ticket$110Cheapest Price
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Questions & Answers

Map of how to get from Louisiana to St. Louis.ExpandLaunch map view
  • Distance: 619.1 mi
  • Duration: 2h 28m

What companies run services between Louisiana, USA and St. Louis, MO, USA?

Southwest Airlines and Delta fly from Louis Armstrong New Orleans International Airport (MSY) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, Greyhound USA operates a bus from New Orleans Bus Station to St Louis Bus Station once daily. Tickets cost $110–220 and the journey takes 14h 40m.

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