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How to get fromLouisville, KY to Detroitby bus (Greyhound), car, plane, or bus

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There are 6 ways to get from Louisville, KY to Detroit by bus (Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Louisville Bus Station to Detroit Bus Stationbus bus Greyhound US0135 / ...
    7h 45m
    $85–130

  2. Drive 358.6 mi

    cheapest
    1. Drive from Louisville, KY to Detroitcar car 358.6 mi
    6h 6m
    $66–95

  3. Fly from Louisville International Airport

    1. Fly from Louisville International Airport (SDF) to Detroit (DTW)plane plane SDF - DTW
    4h 47m
    $79–475

  4. Bus via Columbus

    1. Take the bus from Louisville, KY Bus Station to N Wilson Rd & Ferrell Pl - Columbusbus bus Louisville
    2. Take the bus from Columbus to Detroitbus bus Bsb 33A
    10h 10m
    $80–166

  5. Bus to Covington, fly

    1. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    2. Fly from Covington (CVG) to Detroit (DTW)plane plane CVG - DTW
    6h 18m
    $914–1,350

  6. Bus to Indianapolis, fly

    1. Take the bus from Louisville Bus Station to Indianapolis Union Stationbus bus
    2. Fly from Indianapolis (IND) to Detroit (DTW)plane plane IND - DTW
    6h 51m
    $105–530

Louisville, KY to Detroit by bus

Calendar21Weekly Buses
Duration7h 45mAverage Duration
Ticket$85Cheapest Price
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Questions & Answers

Map of how to get from Louisville, KY to Detroit.ExpandLaunch map view
  • Distance: 365.3 mi
  • Duration: 7h 45m

What companies run services between Louisville, KY, USA and Detroit, MI, USA?

Greyhound USA operates a bus from Louisville Bus Station to Detroit Bus Station twice daily. Tickets cost $60–120 and the journey takes 7h 45m. Jefferson Lines also services this route once daily. Alternatively, Delta flies from Louisville International Airport (SDF) to Detroit (DTW) 4 times a day.

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Bus operators

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