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How to get fromLouisville to Antiochby bus, train, car, or plane

Find Transport to Antioch

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There are 10 ways to get from Louisville to Antioch by bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Louisville, KY to Chicago Union Stationbus bus
    2. Take the train from Chicago Union Station to Antiochtrain train Ncs
    8h 40m
    $56–65

  2. Fly Louisville International Airport to Chicago O'Hare International Airport, train

    cheapest
    1. Fly from Louisville International Airport (SDF) to Chicago O'Hare International Airport (ORD)plane plane SDF - ORD
    2. Take the train from O'Hare Transfer to Antiochtrain train
    5h 45m
    $53–365

  3. Bus, train via Indianapolis

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Antiochtrain train Ncs
    11h
    $89–182

  4. Drive 345.4 mi

    1. Drive from Louisville to Antiochcar car 345.4 mi
    6h 15m
    $63–92

  5. Bus, train via Lafayette

    1. Take the bus from Louisville, KY to Lafayette Amtrak Stationbus bus
    2. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    3. Take the train from O'Hare Transfer to Antiochtrain train Ncs
    9h 21m
    $95–129

  6. Bus, train via Indianapolis #2

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to Antiochtrain train Ncs
    9h 44m
    $56–107

  7. Fly Louisville International Airport to Chicago Midway International Airport, train

    1. Fly from Louisville International Airport (SDF) to Chicago Midway International Airport (MDW)plane plane SDF - MDW
    2. Take the train from Chicago Union Station to Antiochtrain train
    6h 10m
    $60–366

  8. Drive to Blue Grass Airport, fly to Chicago O'Hare International Airport, train

    1. Drive from Louisville to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Chicago O'Hare International Airport (ORD)plane plane LEX - ORD
    3. Take the train from O'Hare Transfer to Antiochtrain train
    5h 43m
    $79–471

  9. Bus to Covington, fly to Chicago O'Hare International Airport, train

    1. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    2. Fly from Covington (CVG) to Chicago O'Hare International Airport (ORD)plane plane CVG - ORD
    3. Take the train from O'Hare Transfer to Antiochtrain train
    7h 49m
    $168–957

  10. Bus to Covington, fly to Chicago Midway International Airport, train

    1. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    2. Fly from Covington (CVG) to Chicago Midway International Airport (MDW)plane plane CVG - MDW
    3. Take the train from Chicago Union Station to Antiochtrain train
    8h 18m
    $170–418

Louisville to Antioch by bus and train

Calendar14Weekly Services
Duration8h 40mAverage Duration
Ticket$56Cheapest Price
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Questions & Answers

Map of how to get from Louisville to Antioch.ExpandLaunch map view
  • Distance: 351.9 mi
  • Duration: 8h 40m

What companies run services between Louisville, KY, USA and Antioch, IL, USA?

There is no direct connection from Louisville to Antioch. However, you can take the bus to Chicago Union Station, walk to Chicago Union Station, then take the train to Antioch. Alternatively, you can take a bus from Louisville, KY to Antioch via Indianapolis Union Station, Indianapolis, and Chicago Union Station in around 11h.

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