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How to get fromLouisville to Appletonby plane, bus (Amtrak, Flixbus), bus, train, car, or bus (Amtrak, Greyhound, Flixbus)

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There are 9 ways to get from Louisville to Appleton by plane, bus (Amtrak, Flixbus), bus, train, car, or bus (Amtrak, Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Appleton International Airport

    best
    1. Fly from Louisville International Airport (SDF) to Appleton International Airport (ATW)plane plane SDF - ATW
    5h 21m
    $86–451

  2. Bus via Indianapolis

    cheapest
    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Appleton Transit Centerbus bus
    12h 25m
    $75–139

  3. Bus

    1. Take the bus from Louisville, KY to Chicago Union Stationbus bus
    2. Take the bus from Chicago Bus Station to Appleton Transit Centerbus bus FlixBus 2550
    11h 39m
    $77–102

  4. Bus, train via Indianapolis

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    4. Take the bus from Milwaukee to Appletonbus bus
    14h 19m
    $109–243

  5. Drive 483.2 mi

    1. Drive from Louisville to Appletoncar car 483.2 mi
    8h 30m
    $89–128

  6. Drive to Blue Grass Airport, fly to Appleton International Airport

    1. Drive from Louisville to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Appleton International Airport (ATW)plane plane LEX - ATW
    5h 17m
    $87–387

  7. Fly Louisville International Airport to Green Bay

    1. Fly from Louisville International Airport (SDF) to Green Bay (GRB)plane plane SDF - GRB
    7h 8m
    $107–476

  8. Fly Louisville International Airport to General Mitchell International Airport, bus

    1. Fly from Louisville International Airport (SDF) to General Mitchell International Airport (MKE)plane plane SDF - MKE
    2. Take the bus from Milwaukee Airport to Appletonbus bus
    8h 38m
    $107–628

  9. Bus, train

    1. Take the bus from Louisville, KY to Chicago Union Stationbus bus
    2. Take the train from Chicago Union Station to Milwaukeetrain train
    3. Take the bus from Milwaukee to Appletonbus bus
    11h 59m
    $86–136

Louisville to Appleton by bus and foot

Calendar5Weekly Services
Duration11h 39mAverage Duration
Ticket$77Cheapest Price
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Questions & Answers

Map of how to get from Louisville to Appleton.ExpandLaunch map view
  • Distance: 455.2 mi
  • Duration: 5h 21m

What companies run services between Louisville, KY, USA and Appleton, WI, USA?

Delta, United Airlines, and American Airlines fly from Louisville International Airport (SDF) to Appleton International Airport (ATW) every 2 hours. Alternatively, you can take a bus from Louisville, KY to Appleton Transit Center via Chicago Union Station and Chicago Bus Station in around 11h 39m.

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