There are 6 ways to get from Louisville to Biloxi by plane, bus (Greyhound), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Louisville International Airport to Gulfport-Biloxi Regional Airport
best- Fly from Louisville International Airport (SDF) to Gulfport-Biloxi Regional Airport (GPT)plane SDF - GPT
5h 57m$147–698Bus (Greyhound)
cheapest- Take the bus from Louisville Bus Station to Montgomery Intermodal Centerbus Greyhound US0112
- Take the bus from Montgomery Intermodal Center to Biloxi Transit Centerbus Greyhound US0602
16h 15m$113–182Drive 669.7 mi
- Drive from Louisville to Biloxicar 669.7 mi
11h 2m$123–177Drive to Blue Grass Airport, fly to Gulfport-Biloxi Regional Airport
- Drive from Louisville to Lexington-Airport-LEXcar
- Fly from Blue Grass Airport (LEX) to Gulfport-Biloxi Regional Airport (GPT)plane LEX - GPT
5h 39m$133–544Fly Louisville International Airport to Mobile Regional Airport, bus
- Fly from Louisville International Airport (SDF) to Mobile Regional Airport (MOB)plane SDF - MOB
- Take the bus from Mobile Bus Station to Biloxi Transit Centerbus
7h 38m$125–547Fly Louisville International Airport to Louis Armstrong New Orleans International Airport, train
- Fly from Louisville International Airport (SDF) to Louis Armstrong New Orleans International Airport (MSY)plane SDF - MSY
- Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain
7h 17m$135–703
Louisville to Biloxi by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Louisville to Biloxi is to bus which costs $110 - $190 and takes 16h 15m.
The fastest way to get from Louisville to Biloxi is to drive and fly which takes 5h 39m and costs $130 - $550.
No, there is no direct bus from Louisville station to Biloxi. However, there are services departing from Louisville Bus Station and arriving at Biloxi Transit Center via Montgomery Intermodal Center. The journey, including transfers, takes approximately 16h 15m.
The distance between Louisville and Biloxi is 593 miles. The road distance is 673.6 miles.
The best way to get from Louisville to Biloxi without a car is to bus which takes 16h 15m and costs $110 - $190.
It takes approximately 5h 57m to get from Louisville to Biloxi, including transfers.
Louisville to Biloxi bus services, operated by Greyhound USA, depart from Louisville Bus Station.
The best way to get from Louisville to Biloxi is to fly which takes 5h 57m and costs $140 - $700. Alternatively, you can bus, which costs $110 - $190 and takes 16h 15m.
Louisville to Biloxi bus services, operated by Greyhound USA, arrive at Montgomery Intermodal Center station.
Biloxi is 1h behind Louisville. It is currently 7:04 PM in Louisville and 6:04 PM in Biloxi.
What companies run services between Louisville, KY, USA and Biloxi, MS, USA?
Delta, American Airlines, and United Airlines fly from Louisville International Airport (SDF) to Gulfport-Biloxi Regional Airport (GPT) every 3 hours. Alternatively, you can take a bus from Louisville Bus Station to Biloxi Transit Center via Montgomery Intermodal Center in around 16h 15m.
- Website
- delta.com
Flights from Louisville International Airport to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $110–650
Flights from Blue Grass Airport to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $85–480
Flights from Louisville International Airport to Mobile Regional Airport via Atlanta
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $90–500
Flights from Louisville International Airport to Louis Armstrong New Orleans International Airport via Atlanta
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $130–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Biloxi Amtrak Sta
- Ave. Duration
- 1h 23m
- Frequency
- Twice daily
- Estimated price
- $20–45
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Louisville Bus Station to Montgomery Intermodal Center
- Ave. Duration
- 10h 40m
- Frequency
- Once daily
- Estimated price
- $75–130
- Website
- Greyhound
Bus from Montgomery Intermodal Center to Biloxi Transit Center
- Ave. Duration
- 4h 35m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Mobile Bus Station to Biloxi Transit Center
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $8–14
- Website
- Greyhound
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Booking & Getting There
Yes, the driving distance between Louisville to Biloxi is 674 miles. It takes approximately 11h 2m to drive from Louisville to Biloxi.
Book your Louisville to Biloxi bus tickets online with Omio and FlixBus.
There are 373+ hotels available in Biloxi.