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How to get fromLouisville to Buffaloby plane, bus, car, or bus (Greyhound)

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There are 7 ways to get from Louisville to Buffalo by plane, bus, car, or bus (Greyhound)

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  1. Fly from Louisville International Airport

    best
    1. Fly from Louisville International Airport (SDF) to Buffalo Niagara International Airport (BUF)plane plane SDF - BUF
    6h 8m
    $134–782

  2. Bus

    cheapest
    1. Take the bus from Louisville, KY Bus Station to Cleveland Ohio Greyhound Stationbus bus Louisville
    2. Take the bus from Cleveland, OH to Buffalo, NYbus bus Cinncinati,OH-Buffalo
    11h 5m
    $53–140

  3. Drive 531.4 mi

    1. Drive from Louisville to Buffalocar car 531.4 mi
    9h 2m
    $97–141

  4. Drive to Blue Grass Airport, fly

    1. Drive from Louisville to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Buffalo Niagara International Airport (BUF)plane plane LEX - BUF
    6h 2m
    $155–898

  5. Bus to Nashville, fly

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Fly from Nashville (BNA) to Buffalo Niagara International Airport (BUF)plane plane BNA - BUF
    7h 24m
    $167–827

  6. Bus via Akron

    1. Take the bus from Louisville, KY Bus Station to Robert K Pfaff Transit Center - Akronbus bus Louisville
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Buffalo, NYbus bus Cinncinati,OH-Buffalo
    11h 35m
    $55–142

  7. Bus via Reading

    1. Take the bus from Louisville, KY Bus Station to Greyhound Station Cincinnatibus bus
    2. Take the bus from Cincinnati Bus Station to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Buffalobus bus
    14h
    $81–189

Louisville to Buffalo by bus

Calendar7Weekly Buses
Duration11h 5mAverage Duration
Ticket$53Cheapest Price
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Questions & Answers

Map of how to get from Louisville to Buffalo.ExpandLaunch map view
  • Distance: 513.2 mi
  • Duration: 6h 8m

What companies run services between Louisville, KY, USA and Buffalo, NY, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Louisville International Airport (SDF) to Buffalo Niagara International Airport (BUF) every 2 hours. Alternatively, you can take a bus from Louisville, KY Bus Station to Buffalo, NY via Cleveland, OH in around 11h 5m.

Airlines
Bus operators

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