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How to get fromLouisville to Cairoby bus, taxi, car, or plane

Find Transport to Cairo

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There are 5 ways to get from Louisville to Cairo by bus, taxi, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi via Nashville

    best
    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Take the taxi from Paducah Bus Station to Cairotaxi taxi
    7h 15m
    $140–196

  2. Drive 249.3 mi

    cheapest
    1. Drive from Louisville to Cairocar car 249.3 mi
    4h 15m
    $46–66

  3. Fly to Barkley Regional Airport, taxi

    1. Fly from Louisville International Airport (SDF) to Barkley Regional Airport (PAH)plane plane SDF - PAH
    2. Take the taxi from Barkley Regional Airport (PAH) to Cairotaxi taxi
    7h 17m
    $152–533

  4. Bus, taxi

    1. Take the bus from Louisville, KY to Evansville, INbus bus
    2. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    4. Take the taxi from Cape Girardeau to Cairotaxi taxi
    10h 37m
    $160–231

  5. Fly to Williamson County Regional Airport, taxi

    1. Fly from Louisville International Airport (SDF) to Williamson County Regional Airport (MWA)plane plane SDF - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to Cairotaxi taxi
    7h 9m
    $202–593

Louisville International Airport (SDF) to Barkley Regional Airport (PAH) flights

Calendar29Weekly Planes
Duration7h 53mAverage Duration
Ticket$86Cheapest Price
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Questions & Answers

Map of how to get from Louisville to Cairo.ExpandLaunch map view
  • Distance: 346.8 mi
  • Duration: 7h 15m

What companies run services between Louisville, KY, USA and Cairo, IL, USA?

There is no direct connection from Louisville to Cairo. However, you can take the bus to Nashville, take the bus to Paducah Bus Station, then take the taxi to Cairo. Alternatively, you can drive from Louisville to Cairo in around 4h 15m.

Airlines
Bus operators
Other operators

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