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How to get fromLouisville to Chapel Hillby plane, bus, bus (Amtrak, Greyhound, Flixbus), train, car, or bus (Greyhound)

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There are 8 ways to get from Louisville to Chapel Hill by plane, bus, bus (Amtrak, Greyhound, Flixbus), train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Raleigh-Durham International Airport, line 800 bus

    best
    1. Fly from Louisville International Airport (SDF) to Raleigh-Durham International Airport (RDU)plane plane SDF - RDU
    2. Take the bus from Regional Transit Center to Pittsboro St at Credit Unionbus bus
    4h 39m
    $88–489

  2. Bus #2

    cheapest
    1. Take the bus from Louisville, KY Bus Station to Columbus - Downtown - Mound Stbus bus
    2. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    3. Take the bus from Coble Transportation Center to N Columbia St at W Franklin Stbus bus 4
    18h 33m
    $87–195

  3. Bus via Atlanta

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Downtown to Durhambus bus
    17h 27m
    $134–237

  4. Bus, train

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Charlottesvilletrain train
    3. Take the train from Charlottesville to Greensborotrain train
    4. Take the bus from Greensboro Depot to N Columbia St at W Franklin Stbus bus 4
    25h 39m
    $271–567

  5. Drive 490.9 mi

    1. Drive from Louisville to Chapel Hillcar car 490.9 mi
    9h 29m
    $90–130

  6. Fly Louisville International Airport to Piedmont Triad International Airport, bus

    1. Fly from Louisville International Airport (SDF) to Piedmont Triad International Airport (GSO)plane plane SDF - GSO
    2. Take the bus from Coble Transportation Center to N Columbia St at W Franklin Stbus bus
    8h 4m
    $131–676

  7. Bus to Covington, fly to Raleigh-Durham International Airport

    1. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    2. Fly from Covington (CVG) to Raleigh-Durham International Airport (RDU)plane plane CVG - RDU
    6h 53m
    $228–491

  8. Bus

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Durhambus bus
    17h 33m
    $126–244

Louisville to Chapel Hill by bus and subway

Calendar4Weekly Services
Duration17h 27mAverage Duration
Ticket$134Cheapest Price
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Questions & Answers

Map of how to get from Louisville to Chapel Hill.ExpandLaunch map view
  • Distance: 440.4 mi
  • Duration: 4h 39m

What companies run services between Louisville, KY, USA and Chapel Hill, Orange County, NC, USA?

You can take a bus from Louisville, KY to E Franklin St at Varsity Theatre via Nashville Bus Station, Atlanta Bus Station, Garnett Station, Civic Center Station, Atlanta Downtown, Durham, and Durham Station in around 17h 27m.

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