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How to get fromLouisville to Columbusby plane, bus, or car

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There are 6 ways to get from Louisville to Columbus by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Golden Triangle Regional Airport

    best
    1. Fly from Louisville International Airport (SDF) to Golden Triangle Regional Airport (GTR)plane plane SDF - GTR
    6h 32m
    $117–488

  2. Drive 405.5 mi

    cheapest
    1. Drive from Louisville to Columbuscar car 405.5 mi
    8h 13m
    $74–107

  3. Bus, drive via Nashville

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    4. Drive from Tupelo to Columbuscar car
    11h 17m
    $89–157

  4. Drive to Blue Grass Airport, fly to Golden Triangle Regional Airport

    1. Drive from Louisville to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Golden Triangle Regional Airport (GTR)plane plane LEX - GTR
    6h 6m
    $143–614

  5. Fly Louisville International Airport to Birmingham–Shuttlesworth International Airport, bus, drive

    1. Fly from Louisville International Airport (SDF) to Birmingham–Shuttlesworth International Airport (BHM)plane plane SDF - BHM
    2. Take the bus from Birmingham-Shuttlesworth to Embassy Suites by Hilton Tuscaloosa Alabama Dowtownbus bus
    3. Drive from Embassy Suites by Hilton Tuscaloosa Alabama Dowtown to Columbuscar car
    8h
    $157–734

  6. Bus, drive

    1. Take the bus from La Tropicana - Louisville, KY to Tornado Bus Co - West Memphisbus bus
    2. Take the bus from Memphis Bus Station to Tupelobus bus
    3. Drive from Tupelo to Columbuscar car
    14h 38m
    $127–268

Louisville International Airport (SDF) to Golden Triangle Regional Airport (GTR) flights

Calendar17Weekly Planes
Duration4h 57mAverage Duration
Ticket$80Cheapest Price
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Questions & Answers

Map of how to get from Louisville to Columbus.ExpandLaunch map view
  • Distance: 382.3 mi
  • Duration: 6h 32m

What companies run services between Louisville, KY, USA and Columbus, MS, USA?

Delta and American Airlines fly from Louisville International Airport (SDF) to Golden Triangle Regional Airport (GTR) twice daily.

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Bus operators

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