What is the cheapest way to get from Louisville to Des Moines?

The cheapest way to get from Louisville to Des Moines is to bus which costs $95 - $170 and takes 13h 10m.

What is the fastest way to get from Louisville to Des Moines?

The fastest way to get from Louisville to Des Moines is to fly which takes 5h 9m and costs $100 - $550.

Is there a direct bus between Louisville and Des Moines?

No, there is no direct bus from Louisville to Des Moines. However, there are services departing from Louisville, KY and arriving at Des Moines via Indianapolis Union Station. The journey, including transfers, takes approximately 13h 10m.

How far is it from Louisville to Des Moines?

The distance between Louisville and Des Moines is 494 miles. The road distance is 584.3 miles.

How do I travel from Louisville to Des Moines without a car?

The best way to get from Louisville to Des Moines without a car is to bus which takes 13h 10m and costs $95 - $170.

How long does it take to get from Louisville to Des Moines?

It takes approximately 5h 9m to get from Louisville to Des Moines, including transfers.

Where do I catch the Louisville to Des Moines bus from?

Louisville to Des Moines bus services, operated by Amtrak Thruway, depart from Louisville, KY station.

Bus or fly from Louisville to Des Moines?

The best way to get from Louisville to Des Moines is to fly which takes 5h 9m and costs $100 - $550. Alternatively, you can bus, which costs $95 - $170 and takes 13h 10m.

Where does the Louisville to Des Moines bus arrive?

Louisville to Des Moines bus services, operated by Amtrak Thruway, arrive at Indianapolis Union Station.

What is the time difference between Louisville and Des Moines?

Des Moines is 1h behind Louisville. It is currently 6:18 AM in Louisville and 5:18 AM in Des Moines.

Can I drive from Louisville to Des Moines?

Yes, the driving distance between Louisville to Des Moines is 584 miles. It takes approximately 9h 46m to drive from Louisville to Des Moines.

How do I get a bus ticket from Louisville to Des Moines?

Book your Louisville to Des Moines bus tickets online with Omio.

Where can I stay near Des Moines?

There are 256+ hotels available in Des Moines.

Louisville to Des Moines - 6 ways to travel via train, plane, bus, and car

How to get fromLouisville to Des Moines

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There are 6 ways to get from Louisville to Des Moines by plane, bus (Amtrak, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly from Louisville International Airport
best
1. Fly from Louisville International Airport (SDF) to Des Moines (DSM)plane SDF - DSM
5h 9m
$105–526
Drive to Blue Grass Airport, fly
cheapest
1. Drive from Louisville to Lexington-Airport-LEXcar
2. Fly from Blue Grass Airport (LEX) to Des Moines (DSM)plane LEX - DSM
5h 50m
$96–422
Bus
1. Take the bus from Louisville, KY to Indianapolis Union Stationbus Nashville
2. Take the bus from Indianapolis Union Station to Des Moinesbus Greyhound US0157S
13h 10m
$98–164
Bus, train
1. Take the bus from Louisville, KY to Indianapolis Union Stationbus
2. Take the train from Indianapolis to Chicago Union Stationtrain
3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
4. Take the bus from Galesburg to Des Moinesbus
17h 51m
$143–359
Drive 580.9 mi
1. Drive from Louisville to Des Moinescar 580.9 mi
9h 46m
$106–154
Drive to Covington, fly
1. Drive from Louisville to Covington (CVG)car
2. Fly from Covington (CVG) to Des Moines (DSM)plane CVG - DSM
5h 20m
$125–598

Louisville to Des Moines by bus

7Weekly Buses

13h 10mAverage Duration

$98Cheapest Price

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Comparing Your Travel Options

Map of how to get from Louisville to Des Moines.

Launch map view

Distance: 491.6 mi
Duration: 5h 9m

What companies run services between Louisville, KY, USA and Des Moines, IA, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Louisville International Airport (SDF) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Louisville, KY to Des Moines via Indianapolis Union Station in around 13h 10m.

Airlines

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