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How to get fromLouisville to Detroitby plane, bus (Greyhound), car, bus, or bus (Amtrak)

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There are 6 ways to get from Louisville to Detroit by plane, bus (Greyhound), car, bus, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Louisville International Airport

    best
    1. Fly from Louisville International Airport (SDF) to Detroit (DTW)plane plane SDF - DTW
    4h 17m
    $79–485

  2. Bus

    cheapest
    1. Take the bus from Louisville, KY Bus Station to Greyhound Station Cincinnatibus bus Louisville
    2. Take the bus from Cincinnati Bus Station to Detroit Bus Stationbus bus Greyhound US0135 / ...
    8h 20m
    $36–114

  3. Drive 357.6 mi

    1. Drive from Louisville to Detroitcar car 357.6 mi
    6h 5m
    $66–95

  4. Drive to Blue Grass Airport, fly

    1. Drive from Louisville to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Detroit (DTW)plane plane LEX - DTW
    4h 10m
    $100–571

  5. Bus to Covington, fly

    1. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    2. Fly from Covington (CVG) to Detroit (DTW)plane plane CVG - DTW
    6h 18m
    $84–527

  6. Bus via Indianapolis

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis, IN to Detroit, MIbus bus Cincinnati
    8h 25m
    $50–114

Louisville to Detroit by bus

Calendar7Weekly Buses
Duration8h 20mAverage Duration
Ticket$36Cheapest Price
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Questions & Answers

Map of how to get from Louisville to Detroit.ExpandLaunch map view
  • Distance: 334 mi
  • Duration: 4h 17m

What companies run services between Louisville, KY, USA and Detroit, MI, USA?

Delta flies from Louisville International Airport (SDF) to Detroit (DTW) 4 times a day. Alternatively, you can take a bus from Louisville, KY Bus Station to Detroit Bus Station via Greyhound Station Cincinnati and Cincinnati Bus Station in around 8h 20m.

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