There are 8 ways to get from Louisville to Duke University by plane, bus, bus (Greyhound, Flixbus), train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Louisville International Airport to Raleigh-Durham International Airport, bus, line 700 bus, line 6 bus
best- Fly from Louisville International Airport (SDF) to Raleigh-Durham International Airport (RDU)plane SDF - RDU
- Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
- Take the bus from Regional Transit Center to Duke St at Jackson Stbus
- Take the bus from Jackson St at Duke St to Flowers Dr at Duke Gardensbus
4h 58m$99–560Drive 495.5 mi
cheapest- Drive from Louisville to Duke Universitycar 495.5 mi
9h 27m$91–131Bus via Atlanta
- Take the bus from Louisville Bus Station to Atlanta Bus Stationbus Greyhound US0135 / ...
- Take the bus from Atlanta Bus Station to Durhambus FlixBus N2471 / ...
17h 16m$120–205Bus, train
- Take the bus from Louisville Bus Station to Indianapolis Union Stationbus
- Take the train from Indianapolis to Charlottesvilletrain
- Take the train from Charlottesville to Greensborotrain
- Take the train from Greensboro to Durham Amtrak Stationtrain
25h 21m$245–532Fly Louisville International Airport to Piedmont Triad International Airport, train
- Fly from Louisville International Airport (SDF) to Piedmont Triad International Airport (GSO)plane SDF - GSO
- Take the train from Greensboro to Durham Amtrak Stationtrain
7h 45m$186–924Bus to Covington, fly to Raleigh-Durham International Airport
- Take the bus from Louisville to Cincinnatibus
- Fly from Covington (CVG) to Raleigh-Durham International Airport (RDU)plane CVG - RDU
7h 13m$109–602Bus
- Take the bus from Louisville to Columbusbus
- Take the bus from Wilson & Ferrell Shell Station - Columbus to Winston Salem(Trans Center)bus
- Take the bus from Coble Transportation Center to N Columbia St at W Franklin Stbus 4
19h 31m$94–177Bus, train via Toledo
- Take the bus from Louisville Bus Station to Toledo Bus Stopbus
- Take the train from Toledo to Raleigh Union Stationtrain
- Take the bus from Union Station - Bus Platform A to Chapel Dr at Duke University Rdbus Drx
29h 16m$271–569
Louisville to Duke University by bus and foot
Questions & Answers
The cheapest way to get from Louisville to Duke University is to drive which costs $90 - $140 and takes 9h 27m.
The fastest way to get from Louisville to Duke University is to fly and bus and line 700 bus and line 6 bus which takes 4h 58m and costs $95 - $600.
No, there is no direct bus from Louisville station to Duke University. However, there are services departing from Louisville Bus Station and arriving at Flowers Dr at Duke Gardens via Atlanta Bus Station and Durham Station. The journey, including transfers, takes approximately 17h 16m.
The distance between Louisville and Duke University is 443 miles. The road distance is 498.4 miles.
The best way to get from Louisville to Duke University without a car is to bus via Atlanta which takes 17h 16m and costs $120 - $210.
It takes approximately 4h 58m to get from Louisville to Duke University, including transfers.
Louisville to Duke University bus services, operated by Greyhound USA, depart from Louisville Bus Station.
Louisville to Duke University bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Louisville to Duke University is 498 miles. It takes approximately 9h 27m to drive from Louisville to Duke University.
There are 396+ hotels available in Duke University.
What companies run services between Louisville, KY, USA and Duke University, NC, USA?
You can take a bus from Louisville Bus Station to Duke University via Atlanta Bus Station, Durham, Durham Station, and Flowers Dr at Duke Gardens in around 17h 16m.
- Website
- aa.com
Flights from Louisville International Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 3h 40m
- When
- Tuesday, Monday, Wednesday, Friday, and Saturday
- Estimated price
- $90–550
Flights from Louisville International Airport to Piedmont Triad International Airport via Charlotte
- Ave. Duration
- 3h 39m
- When
- Every day
- Estimated price
- $140–850
Flights from Louisville International Airport to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Louisville International Airport to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 5h 56m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Louisville International Airport to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 6h 52m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Covington to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $95–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Charlottesville
- Ave. Duration
- 15h 20m
- Frequency
- 3 times a week
- Estimated price
- $160–350
- Website
- Amtrak
Train from Charlottesville to Greensboro
- Ave. Duration
- 3h 33m
- Frequency
- Once daily
- Estimated price
- $45–100
- Website
- Amtrak
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $14–35
- Website
- Amtrak
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $14–35
- Website
- Amtrak
Train from Toledo to Raleigh Union Station
- Ave. Duration
- 19h 52m
- Frequency
- Once daily
- Estimated price
- $220–490
- Website
- Amtrak
- Phone
- +1 919 485 7433
- [email protected]
- Website
- gotriangle.org
Bus from RDU Airport at Terminal 2 to Regional Transit Center
- Ave. Duration
- 12 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- gotriangle.org
- Regular one-way fare
- $3
Bus from Regional Transit Center to Duke St at Jackson St
- Ave. Duration
- 33 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- gotriangle.org
Bus from Union Station - Bus Platform A to Chapel Dr at Duke University Rd
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- gotriangle.org
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide



