Rome2Rio

How to get fromLouisville to Duke Universityby plane, bus, bus (Amtrak, Greyhound, Flixbus), train, car, or bus (Amtrak, Greyhound)

Find Transport to Duke University

See all options

There are 9 ways to get from Louisville to Duke University by plane, bus, bus (Amtrak, Greyhound, Flixbus), train, car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Raleigh-Durham International Airport, bus, line 700 bus, line 6 bus

    best
    1. Fly from Louisville International Airport (SDF) to Raleigh-Durham International Airport (RDU)plane plane SDF - RDU
    2. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    3. Take the bus from Regional Transit Center to Duke St at Jackson Stbus bus
    4. Take the bus from Jackson St at Duke St to Flowers Dr at Duke Gardensbus bus
    4h 58m
    $104–610

  2. Drive  495.5 mi

    cheapest
    1. Drive from Louisville to Duke Universitycar car 495.5 mi
    9h 30m
    $91–131

  3. Bus via Atlanta

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Downtown to Durhambus bus
    17h 1m
    $129–207

  4. Bus, train (Amtrak)

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Charlottesvilletrain train
    3. Take the train from Charlottesville to Greensborotrain train
    4. Take the train from Greensboro to Durham Amtrak Stationtrain train
    25h 46m
    $481–797

  5. Drive to Covington, fly to Raleigh-Durham International Airport

    1. Drive from Louisville to Covington (CVG)car car
    2. Fly from Covington (CVG) to Raleigh-Durham International Airport (RDU)plane plane CVG - RDU
    5h 11m
    $134–732

  6. Fly Louisville International Airport to Piedmont Triad International Airport, train

    1. Fly from Louisville International Airport (SDF) to Piedmont Triad International Airport (GSO)plane plane SDF - GSO
    2. Take the train from Greensboro to Durham Amtrak Stationtrain train
    7h 45m
    $132–519

  7. Bus

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Durhambus bus
    17h 11m
    $129–212

  8. Bus #2

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Columbusbus bus
    3. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    4. Take the bus from Winston Salem(Trans Center) to Durhambus bus
    22h 11m
    $138–226

  9. Bus, train via Arlington (Amtrak)

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Alexandriatrain train
    3. Take the train from Alexandria to Durham Amtrak Stationtrain train
    29h 40m
    $584–975

Louisville to Duke University by bus, subway, and foot

Calendar4Weekly Services
Duration17h 1mAverage Duration
Ticket$129Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Louisville to Duke University.ExpandLaunch map view
  • Distance: 440.6 mi
  • Duration: 4h 58m

What companies run services between Louisville, KY, USA and Duke University, NC, USA?

You can take a bus from Louisville, KY to Duke University via Nashville Bus Station, Atlanta Bus Station, Garnett Station, Civic Center Station, Atlanta Downtown, Durham, Durham Station, and Erwin Rd at Downing St in around 17h 1m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound