There are 7 ways to get from Louisville to Florida Keys by car, plane, bus (Greyhound, Flixbus), shuttle, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Blue Grass Airport, fly to Key West International Airport
best- Drive from Louisville to Lexington-Airport-LEXcar
- Fly from Blue Grass Airport (LEX) to Key West International Airport (EYW)plane LEX - EYW
8h 2m$160–473Bus
- Take the bus from Louisville Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
29h 10m$184–313Drive 1,158.1 mi
- Drive from Louisville to Florida Keyscar 1,158.1 mi
21h 43m$212–306Fly Louisville International Airport to Key West International Airport
- Fly from Louisville International Airport (SDF) to Key West International Airport (EYW)plane SDF - EYW
8h 37m$174–567Fly Louisville International Airport to Miami International Airport, shuttle
- Fly from Louisville International Airport (SDF) to Miami International Airport (MIA)plane SDF - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
9h 30m$274–787Fly Louisville International Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Louisville International Airport (SDF) to Fort Lauderdale–Hollywood International Airport (FLL)plane SDF - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
9h 52m$294–857Bus to Covington, fly to Key West International Airport
- Take the bus from Louisville to Cincinnatibus
- Fly from Covington (CVG) to Key West International Airport (EYW)plane CVG - EYW
8h 59m$189–689
Louisville to Florida Keys by bus and foot
Comparing Your Travel Options
The cheapest way to get from Louisville to Florida Keys is to bus which costs $180 - $320 and takes 29h 10m.
The fastest way to get from Louisville to Florida Keys is to drive and fly which takes 8h 2m and costs $160 - $480.
No, there is no direct bus from Louisville station to Florida Keys. However, there are services departing from Louisville Bus Station and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Atlanta Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 29h 10m.
The distance between Louisville and Florida Keys is 1045 miles. The road distance is 1164.8 miles.
The best way to get from Louisville to Florida Keys without a car is to bus which takes 29h 10m and costs $180 - $320.
It takes approximately 8h 2m to get from Louisville to Florida Keys, including transfers.
Louisville to Florida Keys bus services, operated by Greyhound USA, depart from Louisville Bus Station.
The best way to get from Louisville to Florida Keys is to bus which takes 29h 10m and costs $180 - $320. Alternatively, you can fly, which costs $170 - $600 and takes 8h 37m.
Louisville to Florida Keys bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Louisville to Florida Keys is 1165 miles. It takes approximately 21h 43m to drive from Louisville to Florida Keys.
What companies run services between Louisville, KY, USA and Florida Keys, FL, USA?
You can take a bus from Louisville Bus Station to Florida Keys via Atlanta Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 29h 10m. Alternatively, Delta and American Airlines fly from Louisville International Airport (SDF) to Key West International Airport (EYW) every 4 hours.
- Website
- delta.com
Flights from Blue Grass Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $70–360
Flights from Louisville International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $95–470
Flights from Louisville International Airport to Fort Lauderdale–Hollywood International Airport via Atlanta
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $120–650
Flights from Covington to Key West International Airport via Atlanta
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Louisville Bus Station to Atlanta Bus Station
- Ave. Duration
- 8h 30m
- Frequency
- Every 4 hours
- Estimated price
- $65–110
- Website
- Greyhound
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Once daily
- Estimated price
- $100–170
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $19–35
- Website
- Greyhound
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Booking & Getting There
There are 969+ hotels available in Florida Keys.