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How to get fromLouisville to Fort Myersby plane, bus (Amtrak, Greyhound, Flixbus), car, taxi, bus, or bus (Amtrak, Greyhound)

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There are 7 ways to get from Louisville to Fort Myers by plane, bus (Amtrak, Greyhound, Flixbus), car, taxi, bus, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Ft. Myers

    best
    1. Fly from Louisville International Airport (SDF) to Ft. Myers (RSW)plane plane SDF - RSW
    5h 41m
    $115–608

  2. Bus via Atlanta

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    4. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    22h 15m
    $167–276

  3. Drive  928.3 mi

    1. Drive from Louisville to Fort Myerscar car 928.3 mi
    17h 14m
    $164–237

  4. Drive to Covington, fly to Ft. Myers

    1. Drive from Louisville to Covington (CVG)car car
    2. Fly from Covington (CVG) to Ft. Myers (RSW)plane plane CVG - RSW
    5h 56m
    $250–829

  5. Fly Louisville International Airport to Punta Gorda Airport, taxi

    1. Fly from Louisville International Airport (SDF) to Punta Gorda Airport (PGD)plane plane SDF - PGD
    2. Take the taxi from Punta Gorda Airport (PGD) to Fort Myerstaxi taxi
    4h 20m
    $167–593

  6. Fly Louisville International Airport to Tampa, bus

    1. Fly from Louisville International Airport (SDF) to Tampa (TPA)plane plane SDF - TPA
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    7h 57m
    $123–585

  7. Bus

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Fort Myersbus bus
    22h 40m
    $200–298

Louisville to Fort Myers by bus

Calendar5Weekly Buses
Duration22h 15mAverage Duration
Ticket$167Cheapest Price
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Comparing Your Travel Options

Map of how to get from Louisville to Fort Myers.ExpandLaunch map view
  • Distance: 859.3 mi
  • Duration: 5h 41m

What companies run services between Louisville, KY, USA and Fort Myers, FL, USA?

Southwest Airlines, Breeze Airways, and two other airlines fly from Louisville International Airport (SDF) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from Louisville, KY to Fort Myers Bus Stop via Nashville Bus Station, Atlanta Bus Station, and Tampa Bus Station in around 22h 15m.

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