There are 8 ways to get from Louisville to Frederick by plane, bus, bus (Greyhound), train, car, subway, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Louisville International Airport to Baltimore-Washington International Airport, bus
best- Fly from Louisville International Airport (SDF) to Baltimore-Washington International Airport (BWI)plane SDF - BWI
- Take the bus from Baltimore Airport to Frederick Bus Stationbus
5h 13m$157–663Bus via Columbus
cheapest- Take the bus from Louisville to Columbusbus
- Take the bus from Wilson & Ferrell Shell Station - Columbus to Pittsburgh Intermodal Stationbus
- Take the bus from Pittsburgh Intermodal Station to Frederick Bus Stationbus
13h 25m$79–158Bus, train
- Take the bus from Louisville Bus Station to Indianapolis Union Stationbus
- Take the train from Indianapolis to Washington Union Stationtrain
- Take the train from Washington Union Station to FREDERICK MARC wbtrain
24h 5m$195–476Drive 547.5 mi
- Drive from Louisville to Frederickcar 547.5 mi
9h 41m$100–145Fly Louisville International Airport to Ronald Reagan Washington National Airport, bus
- Fly from Louisville International Airport (SDF) to Ronald Reagan Washington National Airport (DCA)plane SDF - DCA
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
5h 47m$118–712Fly Louisville International Airport to Washington Dulles International Airport, subway, bus
- Fly from Louisville International Airport (SDF) to Washington Dulles International Airport (IAD)plane SDF - IAD
- Take the subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platformsubway
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
6h 24m$88–561Bus to Covington, fly to Baltimore-Washington International Airport, bus
- Take the bus from Louisville to Cincinnatibus
- Fly from Covington (CVG) to Baltimore-Washington International Airport (BWI)plane CVG - BWI
- Take the bus from Baltimore Airport to Frederick Bus Stationbus
7h 17m$202–1,005Bus
- Take the bus from Louisville, KY Bus Station to Robert K Pfaff Transit Center - Akronbus
- Take the bus from Robert K Pfaff Transit Center - Akron to Youngstown Bus Stopbus
- Take the bus from Youngstown Bus Stop to Frederick Bus Stationbus
15h 35m$80–153
Louisville to Frederick by bus
Comparing Your Travel Options
The cheapest way to get from Louisville to Frederick is to bus via Columbus which costs $75 - $160 and takes 13h 25m.
The fastest way to get from Louisville to Frederick is to fly and bus which takes 5h 13m and costs $150 - $700.
No, there is no direct bus from Louisville to Frederick station. However, there are services departing from Louisville and arriving at Frederick Bus Station via Wilson & Ferrell Shell Station - Columbus and Pittsburgh Intermodal Station. The journey, including transfers, takes approximately 13h 25m.
The distance between Louisville and Frederick is 554 miles. The road distance is 550.7 miles.
The best way to get from Louisville to Frederick without a car is to bus via Columbus which takes 13h 25m and costs $75 - $160.
It takes approximately 5h 13m to get from Louisville to Frederick, including transfers.
Louisville to Frederick bus services, operated by Barons Bus, depart from Louisville station.
Louisville to Frederick bus services, operated by Barons Bus, arrive at Columbus station.
Yes, the driving distance between Louisville to Frederick is 551 miles. It takes approximately 9h 41m to drive from Louisville to Frederick.
Book your Louisville to Frederick bus tickets online with Omio.
What companies run services between Louisville, KY, USA and Frederick, MD, USA?
You can take a bus from Louisville to Frederick Bus Station via Wilson & Ferrell Shell Station - Columbus and Pittsburgh Intermodal Station in around 13h 25m.
- Website
- southwest.com
Flights from Louisville International Airport to Baltimore-Washington International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $85–550
Flights from Louisville International Airport to Baltimore-Washington International Airport via Nashville
- Ave. Duration
- 3h 51m
- When
- Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Flights from Louisville International Airport to Ronald Reagan Washington National Airport via Chicago Midway
- Ave. Duration
- 4h
- When
- Tuesday and Wednesday
- Estimated price
- $160–850
Flights from Covington to Baltimore-Washington International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $85–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Washington Union Station
- Ave. Duration
- 18h 29m
- Frequency
- 3 times a week
- Estimated price
- $170–420
- Website
- Amtrak
- Phone
- +1 410-912-6000
- [email protected]
- Website
- BayRunner Shuttle
Bus from Baltimore Airport to Frederick Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $70–110
- Schedules at
- BayRunner Shuttle
Bus from Baltimore Airport to Frederick Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $70–110
- Schedules at
- BayRunner Shuttle
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Booking & Getting There
There are 65+ hotels available in Frederick.








